Ongoing projects

  • 2012 – 2015 - "A novel generation of packaging cell lines for the manufacture of lentivirus based biopharmaceuticals” - PTDC/EBB-BIO/118615/2010, funded by FCT.

  • 2012 – 2015 - "Development of improved suspension MDCK cell lines for the production of viral based bioproducts: manufacturing Influenza and Adenovirus” - PTDC/EBB-EBI/118621/2010, funded by FCT.

  • 2012 – 2015 - "Human central nervous system in vitro models for preclinical research: new tools for studying viral vector-mediated gene” - PTDC/EBB-BIO/119243/2010, funded by FCT.

  • 2012 – 2015 - "Probing adenovirus-host cell interactions: a systems biotechnology approach to improve production of gene delivery vectors” - PTDC/EBB-BIO/119501/2010, funded by FCT.

  • 2011 – 2014 - "Stem cell generation and manipulation by nanoparticle mediated gene transfer for the safe clinical application of gene-modified cells” – ENMED/0001/2010, financiado pela iniciativa EuroNanoMed ERA-Net.

  • 2011 – 2015 "CompexINC "- New Technologies and Production Tools for Complex Protein Biologics.  FP7 / SME-targeted research for developing tools and technologies for high-throughput research, funded by EU. http://eurice.eu/projects/life-sciences/complexinc/

  • 2011-2016 - "PREDECT” – New Models for Preclinical Evaluation of Drug Efficacy in common solid tumours" - GRANT AGREEMENT No. 115188, funded by IMI (Innovative Medicines Initiative) Joint Undertaking, funded by EU. www.predect.eu

  •  2011-2014 - "3D in vitro models for reducing animal experimentation in pharmaceutical development: integrative approaches for prediction of hepatic drug metabolism and neurotoxicity" - PTDC/EBB-BIO/112786/2009

  • 2010 – 2015 - "Cardio Repair European Multidisciplinary Initiative” - HEALTH-F5-2010-242038, funded by EU

  • 2010 – 2012– "2D fluorometry: a powerful tool to improve mammalian cell process development” - PTDC/EBB-EBI/102750/2008, funded by FCT

  • 2010-2012 – "Novel Cell Factories for the production of secreted complex bioproducts: a syntetic biology approach for improved product Stoichiometries” - PTDC/EBB-EBI/102266/2008, funded by FCT

  • 2010-2012 – "BACULOME-Engineering cellular energetics for improvement of bioprocesses: metabolic modeling for enhanced vaccines production” - PTDC/EBB-EBI/103359/2008, funded by FCT

  • 2010-2012 - "Retroviral like particles: improving potential as candidate vaccines for Hepatitis C” - PTDC/EBB-BIO/102649/2008, funded by FCT

  • 2010-2012 – "Using functional genomics to improve mammalian cells for virus based biopharmaceuticals manufacture” - PTDC/EBB-BIO/100491/2008, funded by FCT

  • 2010-2012 – "Preconditioning triggered by Carbon monoxide: new strategies to prevent brain damage due to hypoxia-ischemia and reperfusion” - PTDC/SAU-NEU/098747/2008, funded by FCT

  • 2009-2012 - "HYPERLAB - high yield and performance stem cell lab", funded by EU (223011)

  • 2009-2012 - "Integrated strategies for expansion, neuronal differentiation and cryopreservation of human embryonic stem cells", funded by FCT (PTDC/BIO/72755/2006)

  • 2008-2012 - "BrainCAV: Gene Transfer for Brain Therapy", funded by EU (FP7-222992)

  • 2007-2010 - "Fundamentals of downstream processing of enveloped viruses: towards an integration of purification processes", funded by FCT (PTDC/EQU-EQU/71645/2006)

  • 2006-2011 - "CLINIGENE-NoE: European Network for the Advancement of Clinical Gene Transfer and Therapy", funded by EU (LSHB-CT-2006-018933)

  • 2007-2010 - "Manufacturing canine adenovirus vectors for gene therapy: development of MDCK CAV-2E1- transcomplementing cell lines", funded by FCT (PTDC/BIO/69452/2006)

  • 2007-2010 - "Development of flexible cell lines for the Production of Retrovirus and Lentivirus for Gene Therapy", funded by FCT (PTDC/BIO/69451/2006)

  • 2007-2010 - "Novel stroke model for neuroprotective research: bioreaction of primary brain cell aggregates", funded by FCT (PTDC/BIO/69407/2006)

  • 2007-2010 - "Carbon monoxide as a neuroprotective agent against hypoxia-ischemia and reperfusion”, funded by FCT, Portugal (PTDC/SAU-NEU/64327/2006)