The main area of activities is the pharmaceutical industry (human and veterinary), namely in the development of production processes for new vaccines, diagnostics and therapeutic products, as well as production of recombinant proteins for structural biology studies

Another relevant area of work is the agro industry, namely in the development of Probiotics and starter cultures.

Pilot Plant Track Record

  • Biopharmaceutical Products
    Cephalosporin C - Optimization of production
    Recombinant fusion protein for cancer therapy
    Antibodies fragments for cancer therapy – optimization of production process using Pichia pastoris (methanol induced and constitutive expression)
    Malaria proteases inhibitors

  • Vaccine development
    Recombinant proteins for use in subunits vaccines
    Virus like particles (VLP's) candidate vaccines for HIV and Porcine Parvovirus
    Bacterial vaccines for veterinary purposes (Canine Leptospirose, Strangles)
    Mass production of endothelial cells for Cowdriose vaccine

  • Diagnostics
    Diagnostic prototype for HIV
    Diagnostic prototype for Leishmania
    Antibody fragment for cancer

  • Cell and virus banking for Quality Control purposes (Bioassays)

  • Production and purification of proteins for Structure Function Research
    Nuclear Receptors and their ligand bindings domains
    Non glycosilated proteins from E.coli
    Glycoproteins from animal cells

  • Starter Cultures for Biotechnological Processes
    Leuconostoc oenus
    Lactobacillus plantarum
    Bacillus subtilis spores for use as probiotics

  • Liophilization of Medicinal and Aromatic Plants