IBET - Instituto de Biologia Experimental e Tecnologia

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• National Contact Point
• Antibiotic stress and virulence of enterococci
• Applied and environmental mycology
• Biochemical engineering laboratory
• Biomolecular diagnostics laboratory
• Bioseparation laboratory
• Control of Gene Expression
• Laboratory of Membrane Processes
• Microbial and enzyme technology laboratory
• Pharmacokinetics and Biopharmaceutical Analysis
• Plant cell biotechnology laboratory
• Systems biology and engineering

Research Interests

• Recovery of molecules with biological activity from complex media;
• Development of membrane separation processes and membrane (bio)reactors;
• Development of techniques for on-line, real-time, in-vivo and at molecular scale monitoring.

Main publications

• "Probing the change of enzymatic activity of horseradish peroxidase induced by membrane permeation using tryptophan fluorescence”. C. A. M. Portugal, J.C. Lima, J.G. Crespo. J. Memb. Sci. 284 (1-2), 180-192, 2006.
• "Direct integration of pervaporation as a sample preparation method for a dedicated "electronic nose"” C. Pinheiro, T. Schafer, J. G. Crespo. Anal. Chem. 77 (15), 4927-4935, 2005.
• "Membrane bioreactors for the removal of anionic micropollutants from drinking water” J. G. Crespo, S. Velizarov, M. A. M. Reis. Curr. Op. Biotech. 15 (5), 463-468, 2004.
• "Supported liquid membranes using ionic liquids: study of stability and transport mechanisms” R. Fortunato, C. A. M. Afonso, M. A. M. Reis, J. G. Crespo. J. Memb. Sci. 242 (1-2), 197-209, 2004.
• "Two-dimensional fluorometry coupled with artificial neural networks: A novel method for on-line monitoring of complex biological processes” G. Wolf, J. S. Almeida, C. Pinheiro, V. Correia, C. Rodrigues, M. A. M. Reis, J. G. Crespo . Biotech. Bioeng. 72 (3), 297-306, 2001.

Ongoing Projects

Prometheus Project - Productive on-site membrane and evaporator treatment of high organic load effluents.

Contacts