2017

João B. Vicente, Henrique G. Colaço, Francesca Malagrinò, Paulo E. Santo, André Gutierres, Tiago M. Bandeiras, Paula Leandro, José A. Brito, Alessandro Giuffrè
A Clinically Relevant Variant of the Human Hydrogen Sulfide-Synthesizing Enzyme Cystathionine β-Synthase: Increased CO Reactivity as a Novel Molecular Mechanism of Pathogenicity?
Oxid Med Cell Longev. 2017;2017:8940321 More info

Lobo SA, Videira MA, Pacheco I, Wass MN, Warren MJ, Teixeira M, Matias PM, Romão CV, Saraiva LM
Desulfovibrio vulgaris CbiKP cobaltochelatase: evolution of a haem binding protein orchestrated by the incorporation of two histidine residues
Environ Microbiol. 2017 Jan;19(1):106-118 More info

T. L. Clarke, M. P. Sanchez-Bailon, K. Chiang, J. J. Reynolds, J. Herrero-Ruiz, T. M. Bandeiras, P. M. Matias, S. L. Maslen, J. M. Skehel, G. S. Stewart, and C. C. Davies, C. C.
PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination
Mol Cell. 2017 Mar 2;65(5):900-916.e7 More info

2016

Celia Valente Romao, Joao B Vicente, Patricia T Borges, Bruno L Victor, Pedro Lamosa, Elisio Silva, Luis Pereira, Tiago M Bandeiras, Claudio M Soares, Maria A Carrondo, David Turner, Miguel Teixeira, Carlos Frazao
Structure of Escherichia coli Flavodiiron nitric oxide reductase
J Mol Biol. 2016 Nov 20;428(23):4686-4707 More info

H.G. Colaço, P.E. Santo, P.M. Matias, T.M. Bandeiras, J.B. Vicente
Roles of Escherichia coli ZinT in cobalt, mercury and cadmium resistance and structural insights into the metal binding mechanism
Metallomics. 8:327-336  More info

2015

J.P. Leite, M. Duarte, A.M. Paiva, F. Ferreira-da-Silva, P.M. Matias, O.C. Nunes, L. Gales
Structure-guided engineering of molinate hydrolase for the degradation of thiocarbamate pesticides
PLoS One 10:e0123430. More info

Lamosa P, Lourenço EC, d'Avó F, Nobre A, Bandeiras TM, da Costa MS, Ventura MR, Santos H.
A unique glyceryl diglycoside identified in the thermophilic, radiation-resistant bacterium Rubrobacter xylanophilus.
PLoS One 10:e0123430. More info

N. Zaarur, X. Xu, P. Lestienne, A.B. Meriin, M. McComb, C.E. Costello, G.P. Newnam, R. Ganti, N.V. Romanova, M. Shanmugasundaram, S.T. Silva, T.M. Bandeiras, P.M. Matias, K.S. Lobachev, I.K. Lednev, Y.O. Chernoff, M.Y. Sherman
RuvbL1 and RuvbL2 enhance aggresome formation and disaggregate amyloid fibrils
EMBO J., 112(37):11455-11460 More info

P.M. Matias, S.H. Baek, T.M. Bandeiras, A. Dutta, W.A. Houry, O. Llorca, J. Rosenbaum
The AAA+ proteins Pontin and Reptin enter adult age: From understanding their basic biology to the identification of selective inhibitors
 Frontiers in Molecular Biosciences 2:17 More info

2014

N. Borges, C. Jorge, L. Gonçalves, S. Gonçalves, P. Matias and H. Santos
Mannosylglycerate: structural analysis of biosynthesis and evolutionary history
Extremophiles 18:835-852 More info

S. P. Miller, S. Gonçalves, P. M. Matias, and A. M. Dean
Evolution of a Transition State: Role of Lys100 in the Active Site of Isocitrate Dehydrogenase
ChemBioChem, 15:1145-1153 More info

2013

J. Rosenbaum, S.H. Baek, A. Dutta, W.A. Houry, O. Huber, T.R. Hupp,  P.M. Matias
The Emergence of the Conserved AAA+ ATPases Pontin and Reptin on the Signaling Landscape
Sci. Signal. 6:mr1.  More info

M. C. Marques, R. Coelho, I. A. C. Pereira, P. M. Matias
Redox state-dependent changes in the crystal structure of [NiFeSe] hydrogenase from Desulfovibrio vulgaris Hildenborough
Int. J. Hydrogen Energ. 38(21):8664–8682.  More info

P. Nogly, P. M. Matias, M. de Rosa, R. Castro, H. Santos, A. R. Neves and M. Archer
High-resolution structure of an atypical a-phosphoglucomutase related to eukaryotic phosphomannomutases
Acta Crystallogr. D 69:2008:2016  More info

T.M Bandeiras, M.C. Freitas, D. Petrasch, A. Kletzin and C. Frazão
SAD phasing towards structure determination of thermostable Rieske ferrodoxin with a novel stabilizing disulfide bridge
Acta Crystallogr. F69(5):555-558 More info

2012

S. Gonçalves, S. P. Miller, M. A. Carrondo, A. M. Dean and P. M. Matias
Induced Fit and the Catalytic Mechanism of Isocitrate Dehydrogenase
Biochemistry, 51:7098–7115. DOI:10.1021/bi300483w

Carvalho-Santos Z, Machado P, Alvarez-Martins I, Gouveia SM, Jana SC, Duarte P, Amado T, Branco P, Freitas MC, Silva ST, Antony C, Bandeiras TM, Bettencourt-Dias
BLD10/CEP135 Is a Microtubule-Associated Protein that Controls the Formation of the Flagellum Central Microtubule Pair
Dev Cell 23(2):412-424. DOI:10.1016/j.devcel.2012.06.001

Santos SP, Bandeiras TM, Pinto AF, Teixeira M, Carrondo MA, Romão CV
Thermofluor-based optimization strategy for the stabilization and crystallization of Campylobacter jejuni desulforubrerythrin
Protein Expr Purif. 2012, Feb;81(2):193-200. More info

2011

C. S. A. Baltazar, M. C. Marques, C. M. Soares, A. M. DeLacey, I. A. C. Pereira and P. M. Matias
Nickel-Iron-Selenium Hydrogenases - An Overview
Eur. J. Inorg. Chem., 2011(7):948-962. DOI:10.1002/ejic.201001127

C. V. Romão, D. Ladakis, S. A. L. Lobo, M. A.Carrondo, A. A. Brindley, E. Deery, P. M. Matias, R. W. Pickersgill, L. M. Saraiva and Martin J. Warren
Evolution in a family of chelatases facilitated by the introduction of active site asymmetry and protein oligomerization
PNAS 108(1):97-102. DOI:10.1073/pnas.1014298108

S. Gonçalves, A. M. Esteves, H. Santos, N. Borges and P. M. Matias
The three-dimensional structure of mannosyl-3-phosphoglycerate phosphatase from Thermus thermophilus HB27: a new member of the Haloalcanoic Acid Dehalogenase Superfamily
Biochemistry, in press doi:10.1021/bi201171h

S. Gonçalves, A. M. Esteves, N. Borges, H. Santos and P. M. Matias
Crystallization and preliminary X-ray analysis of mannosyl-3-phosphoglycerate phosphatase from Thermus thermophilus HB27
Acta Cryst. F67:390-396. DOI:10.1107/S1744309111002843

Pinho FG, Pinto AF, Pinto LC, Huber H, Romão CV, Teixeira M, Matias PM, Bandeiras TM.
Superoxide reductase from Nanoarchaeum equitans: expression, purification, crystallization and preliminary X-ray crystallographic analysis.
Acta Cryst. F 2011 May 1;67(Pt 5):591-5 More info

S. Gorynia, T. M. Bandeiras, F. G. Pinho, C. E. McVey, C. Vonrhein, A. Round, D. I. Svergun, P. Donner, P. M. Matias and M. A. Carrondo
Structural and functional insights into a dodecameric molecular machine – The RuvBL1/RuvBL2 complex
J. Struct. Biol., 176(3):279-291.  More info

2010

F. G. Pinho, C. V. Romão, A. F. Pinto, L. M. Saraiva, H. Huber, P. M. Matias, M. Teixeira, T.M. Bandeiras
Cloning, purification, crystallization and X-ray crystallographic analysis of Ignicoccus hospitalis neelaredoxin
Acta Cryst. F66:605–607. DOI:10.1107/ S1744309110012030

M. C. Marques, R. Coelho, A. L. De Lacey, I. A.C. Pereira, P. M. Matias
The three-dimensional structure of [NiFeSe] Hydrogenase from Desulfovibrio vulgaris Hildenborough: a Hydrogenase without a bridging ligand in the active site in its oxidised,as-isolated state
J. Mol. Biol. 396:893-907. DOI: 10.1016/j.jmb.2009.12.013

S. Gonçalves, N. Borges, A. M. Esteves, B. Victor, C. M. Soares, H. Santos, P. M. Matias
Structural analysis of Thermus thermophilus HB27 mannosyl-3-phosphoglycerate synthase provides evidence for a second catalytic metal ion and new insight into the retaining mechanism of glycosyltransferases
J. Biol. Chem. 285(23):17857-17868. DOI:10.1074/jbc.M109.095976

T. M. Bandeiras, C. V. Romão, J. V. Rodrigues, M.Teixeira, P. M. Matias
Purification,crystallization and X-ray crystallographic analysis of Archaeoglobus fulgidus neelaredoxin
Acta Cryst. F66: 316-319. DOI: 10.1107/S1744309110000916.

M. C. Marques, R. Coelho, A. L. De Lacey, I. A.C. Pereira, P. M. Matias
The three-dimensional structure of [NiFeSe] Hydrogenase from Desulfovibrio vulgaris Hildenborough: a Hydrogenase without a bridging ligand in the active site in its oxidised,as-isolated state
J. Mol. Biol. 396:893-907.  More info

2008

T.M. Bandeiras, R.C. Hillig, P.M. Matias, U. Eberspaecher, J. Fanghänel, M. Thomaz, S. Miranda, K. Crusius, V. Pütter, P. Amstutz, M. Gulotti-Georgieva, H.K. Binz, C. Holz, A.A.P. Schmitz, C. Lang, P. Donner, U. Egner, M.A. Carrondo and B. Müller-Tiemann
Crystal structure of Wild-Type Plk-1 Kinase Domain in Complex with a Selective DARPin
Acta Crystallogr., D64:339-353

2007

M. Matzapetakis, P. Turano, E.C. Theil, I. Bertini
(13)C-(13)C NOESY spectra of a 480 kDa protein: solution NMR of ferritin
J. Biomol. NMR, 38:237-242

2006

C. Frazão, C.E. McVey, M. Amblar, A. Barbas, C. Vonrhein, C.M. Arraiano and M.A. Carrondo
Unravelling the dynamics of RNA degradation by RNAse II and its RNA- bound complex
Nature 443: 110-114

M. Roxo-Rosa, Z. Xu, A. Schmidt, M. Neto, Z.W. Cai, C.M. Soares, D.N., Sheppard and M.D. Amaral
Revertant mutants G550E and 4RK rescue cystic fibrosis mutants in the first nucleotide-binding domain of CFTR by different mechanisms
PNAS 103:17891-17896

P.M. Matias, S. Gorynia, P. Donner, M.A. Carrondo
Crystal Structure of the Human AAA+ Protein RuvBL1
J. Biol. Chem.281:38918-38929

Patent no. WO 01/66599, filed 2001.