Research Fellowship (MSc) – Advanced Cell Model

Instituto de Biologia Experimental e Tecnológica (iBET), has an open position for a research fellowship in the field of Biomedical Research available within the project hematoPRO: Building a road map for Hematopoietic-Progenitor differentiation from human induced pluripotent stem cells (hiPSC): Towards novel cell tools for immunotherapy and immune competent preclinical models.“ Ref. 785/iBETXplore call 2023, financed by iBETXplore call 2023

Master in Biological, Chemical or Biomedical Engineering, Biotecnology, Biology, Biochemistry, Immunology or equivalent (16/20 or higher).

We seek a motivated candidate willing to work both collaboratively but also independently. Good use of the English language (written, spoken).

We particularly value:

1) mammalian or human induced pluripotent cells (preferencially);

2) Hands on experience with 3D cultures/organoids

3) Analyticals for cell and heterotypic culture characterization (multicolor flow cytometry; microscopy; RT-PCR; immunofluorescence, Western Blot).

4) Experience with software for data analysis and visualization (e.g., GraphPad Prism, ImageJ, FlowJo)

5) Good use of the English language both written and spoken

6) Reading and interpreting scientific literature

7) Analysis, discussion, and presentation of scientific data

The candidate will contribute to the project with optimization of hiPSC differentiation protocols to macrophages (iMAC) and endothelial cells (iEC) and respective functional attributes. The candidate will be generating heterotypic 3D cell models by combining iMACs and iECs with tumor cells. Activities incluse differentitationa nd characterization of iMACs and iECs; establishment of heterptypic 3D models in stirred tank bioreactors; interaction with researchers from different labs and expertise at iBET.

The fellowship will have a duration of 6 months, eventually renewed until the end of project, without prejudice of the maximum limits foreseen by law. The expected starting date is 14 of November of 2024.

Apply now with your detailed CV, motivation letter, and diploma certificates to jobs@ibet.pt, referring to the job reference in the subject of the email “Ref.785/iBETXplorecall2023”.