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May 11, 2020

iBET participates in NESSIE, an ERA-NET project for materials research and innovation aimed at increasing the efficiency of vaccine purification using ceramic 3D printing. The project adresses the slow and expensive development and production processes for essential vaccines, a limitation which has been emphasised by the current COVID-19 pandemic.

The goal of this project is to produce chromatographic devices to purify complex biopharmaceutical compounds and accelerate time to market for vaccines and gene therapy products.

By developing a novel purification system, NESSIE project is able to improve separation thus, reducing the costs of vaccine production. By improving the process and lowering the costs this project will enable vaccines to become more readily available to low-income countries .

The new process is centered around ceramic 3D printed chromatographic columns. These columns are designed to improve the separation of impurities during the early stages of vaccine creation. This can reduce the number of purification steps, and therefore the associated production time and costs.

Novel chromatographic columns. Credit: SINTEFweb, YouTube

NESSIE has successfully produced the first chromatographic supports and will soon test it for purification of adenovirus, which are excellent vectors for delivering genes or vaccine antigens to humans. Read the press release here.

Coordinated by SINTEF, the NESSIE project gathers expertise from other 4 institutions: iBET, GenIbet, Cerpotech and Lithoz.

The project is supported by M-era.Net and National Funding Agencies. To learn more about NESSIE project, click here.

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