Projects

iBET has been involved in some of the most prestigious RD&I and technology transfer projects, with remarkable impact internationally at many scientific and technological domains.
Filters
sustainability-food-health concluded international

INIAV, ITQB NOVA, Casa do Arroz, Ernesto Morgado, Mater Dynamics, BGI, Grupo Desarrollo, IATA, Alexandria Univ.

TRACE-RICE – Tracing Rice and Valorizing Side Streams along Mediterranean Blockchain
European Comission
March 12, 2020 — April 11, 2024
sustainability-food-health concluded national

phages4ACB – Hunting Bacteriophages for Food and Beverages Biopreservation
FCT - Fundação para a Ciência e Tecnologia
December 07, 2022 — February 28, 2025
biopharma concluded international

CRUZIVAX – Vaccine for Prevention and Treatment of Trypanosoma Cruzi Infection
European Comission
June 01, 2019 — May 31, 2024

Concluded Projects (Previous to 2020)

  • CARDIOCONTRACT: Automated Cardiomyocyte Contractility Assay Instrument.
    2018-2020, EUROSTARS-2 – 12529/19/Q
  • DiViNe – Sustainable downstream processing of vaccines through incorporation of nanobiotechnologies: novel affinity ligands and biometric membranes.
    2015-2019, H2020-LEIT-BIO-1-635770. Funded by the EU
  • INNOVATE – Investigating the Novel Valuable bio-therapeutics and expression systems.
    2014-2017, ERA-IB-2/0007/2013, Funded by the EU
  • EDUFLUVAC – Combinatorial immunization strategy to educate the immune system towards cross recognition and coverage against antigenic drift in seasonal influenza virus exposure.
    2013-2017, FP7-HEALTH-2013-INNOVATION. Funded by the EU.
  • EPIGENESIS – One Health approach to integrate Guadeloupe research on vector-borne and emerging diseases in the ERA.
    2013-2016, FP7-REGPOT-2012-2013-1, funded by the EU.
  • BRAINVECTORS— From Brain Gene Transfer Towards Gene Therapy: Pharmacological Assessment of AAV, CAV and LVV.
    2012-2016, FP7-PEOPLE-2011-IAPP. Funded by the EU.
  • SpeCCC – Specialised Cell Carrier Components.
    2012-2015, FP7‐SME‐2012‐315717. Funded by the EU
  • NanoGene – Stem cell generation and manipulation by nanoparticle mediated gene transfer for the safe clinical application of gene-modified cells.
    2011-2014, ENMED/0001/2010, funded by EuroNanoMed ERA-Net.
  • PREDECT – New Models for Preclinical Evaluation of Drug Efficacy in common solid tumours.
    2011-2016, GRANT AGREEMENT No. 115188, funded by IMI (Innovative Medicines Initiative) Joint Undertaking, funded by EU.
  • ComplexINC – New Technologies and Production Tools for Complex Protein Biologics.
    2011-2015, FP7 / SME-targeted research for developing tools and technologies for high-throughput research, funded by EU.
  • CAREMI – Cardio Repair European Multidisciplinary Initiative.
    2010-2015, HEALTH-F5-2010-242038, funded by EU
  • HYPERLAB – high yield and performance stem cell lab.
    2009-2012, funded by EU (223011)
  • BrainCAV: Gene Transfer for Brain Therapy.
    2008-2012, funded by EU (FP7-222992)
  • CLINIGENE-NoE: European Network for the Advancement of Clinical Gene Transfer and Therapy.
    2006-2011, LSHB-CT-2006-018933, funded by the EU
  • VITROCELLOMICS – Reducing Animal Experimentation in Preclinical Predictive Drug Testing by Human Hepatic in vitro Models Derived from Embryonic Stem Cells.
    2006-2009, funded by EU (LSHB-CT-2006-018940)
  • BACULOGENES – Baculovirus Vectors for Gene Therapy.
    2006-2009, FP6 – 2007, funded by the EU
  • MARKVAC – Development of marker vaccines, companion diagnostic tests and improvement of epidemiological knowledge to facilitate control of rinderpest and peste des petits ruminants viruses.
    2005-2007, RP/PPR MARKVAC, funded by the EU
  • EPIGENEVAC – Epidemiology and new generation vaccines for Ehrlichia and Anaplasma infections of ruminants.
    2005-2009, FP6-003713-INCO-DEV-1, funded by the EU
  • CELLPROM – Cell Programming by Nanoscaled Devices.
    2004-2009, NMP4-CT-2004-500039, funded by the EU
  • INSERTAGENE – Integrated Strategies for efficient therapeutic retrovirus based on modular cell lines.
    2003-2005, QLK3-CT-2002-01949, funded by the EU
  • ROTASAFE – Novel strategies for a safe rotavirus vaccine.
    2003-2005, QLRT-2001-01249, funded by the EU
  • COWDRIA – Mass production of Cowdria ruminantium to produce a cost effective veterinary vaccine against heartwater.
    2001-2004, 8-ACP-TPS-040, funded by the EU
  • ORALVAC – Development of Oral Vaccines, Role of Wildlife in The Maintenance of these Diseases.
    2001-2004, ICA4-CT-2000-30027, funded by the EU
  • ERAdicatPH: Understanding primary hyperoxaluria type 1 towards the development of innovative therapeutic strategies.
    2016-2019, E-Rare3/0002/2015, funded by FCT, Portugal
  • Therapeutic Targets for Triple Negative Breast Cancer: Development of mono and bispecific antibodies against Notch1 ligands.
    2016-2019, PTDC/BBB-BMD/4497/2014, funded by FCT, Portugal
  • NETDIAMOND: New targets in diastolic heart failure: from comorbidities to personalized medicine.
    2016-2019, POCI-01-0145-FEDER-016385
  • CardioRegen: Integrative studies from the embryo to Scalable Multipronged Generation of hESC-derived Myocardial progenitors for heart repair.
    2015-2019, HMSP-ICT/0039/2013, HMS program, funded by FCT, Portugal
  • Engineering biosensors for human cell type and state diagnosis using synthetic digital computation.
    2018-2019, MIT-EXPL/BIO/0097/2017
  • Establishment of a flexible insect cell platform for fast production of pseudo-typed VLPs for drug and vaccine development.
    2014-2015, EXPL/BBB-BIO/1541/2013, funded by FCT, Portugal
  • Molecular approaches to develop an insect cell production system for Hepatitis C vaccine candidate.
    2014-2015, EXPL/BBB-BIO/1129/2013, funded by FCT, Portugal
  • Development of a scalable strategy for stem cells purification.
    2013-2014, EXPL/BBB-EBI/1003/2012, funded by FCT, Portugal.
  • Systems biotechnology for improved production of biopharmaceuticals in animal cells.
    2013-2015, PTDC/BBB-BSS/0518/2012, funded by FCT, Portugal.
  • Combining siRNA and AAV therapy approaches to target human basal-like breast cancer: from vector development to anti-tumor efficacy evaluation.
    2013-2015, PTDC/BBB-BIO/1240/2012, funded by FCT, Portugal.
  • Integrative approaches to depict human cardiac stem cell receptome and its role in the cardiac regenerative process.
    2013-2015, PTDC/BBB-BIO/1414/2012, funded by FCT, Portugal.
  • A novel generation of packaging cell lines for the manufacture of lentivirus based biopharmaceuticals.
    2012-2015, PTDC/EBB-BIO/118615/2010, funded by FCT, Portugal.
  • Development of improved suspension MDCK cell lines for the production of viral based bioproducts: manufacturing Influenza and Adenovirus.
    2012-2015, PTDC/EBB-EBI/118621/2010, funded by FCT, Portugal.
  • Human central nervous system in vitro models for preclinical research: new tools for studying viral vector-mediated gene.
    2012-2015, PTDC/EBB-BIO/119243/2010, funded by FCT, Portugal.
  • Probing adenovirus-host cell interactions: a systems biotechnology approach to improve production of gene delivery vectors.
    2012-2015, PTDC/EBB-BIO/119501/2010, funded by FCT, Portugal.
  • Development of function blocking antibodies using Phage Display Technology: Inhibiton of the Notch1 signaling pathway by function blocking anti-jagged 1 antibody.
    2012-2016, PTDC/SAU-ONC/121670/2010, funded by FCT, Portugal
  • MSVida: The architecture of life – Probing the quaternary structure of virus capsids by native mass spectrometry.
    2012-2016, RECI/BBB-BEP/0104/2012, funded by FCT, Portugal
  • 3D in vitro models for reducing animal experimentation in pharmaceutical development: integrative approaches for prediction of hepatic drug metabolism and neurotoxicity.
    2011-2014, PTDC/EBB-BIO/112786/2009, funded by FCT, Portugal.
  • Preconditioning triggered by Carbon monoxide: new strategies to prevent brain damage due to hypoxia-ischemia and reperfusion.
    2010-2012, PTDC/SAU-NEU/098747/2008, funded by FCT, Portugal.
  • 2D fluorometry: a powerful tool to improve mammalian cell process development.
    2010-2012, PTDC/EBB-EBI/102750/2008, funded by FCT, Portugal.
  • Novel Cell Factories for the production of secreted complex bioproducts: a syntetic biology approach for improved product Stoichiometries.
    2010-2012, PTDC/EBB-EBI/102266/2008, funded by FCT, Portugal.
  • BACULOME-Engineering cellular energetics for improvement of bioprocesses: metabolic modeling for enhanced vaccines production.
    2010-2012, PTDC/EBB-EBI/103359/2008, funded by FCT, Portugal.
  • Retroviral like particles: improving potential as candidate vaccines for Hepatitis C.
    2010-2012, PTDC/EBB-BIO/102649/2008, funded by FCT, Portugal.
  • Using functional genomics to improve mammalian cells for virus based biopharmaceuticals manufacture.
    2010-2012, PTDC/EBB-BIO/100491/2008, funded by FCT, Portugal.
  • Integrated strategies for expansion, neuronal differentiation and cryopreservation of human embryonic stem cells.
    2009-2012, funded by FCT (PTDC/BIO/72755/2006)
  • Fundamentals of downstream processing of enveloped viruses: towards an integration of purification processes.
    2007-2010, funded by FCT (PTDC/EQU-EQU/71645/2006)
  • Manufacturing canine adenovirus vectors for gene therapy: development of MDCK CAV-2E1- transcomplementing cell lines.
    2007-2010, funded by FCT (PTDC/BIO/69452/2006)
  • Development of flexible cell lines for the Production of Retrovirus and Lentivirus for Gene Therapy.
    2007-2010, funded by FCT (PTDC/BIO/69451/2006)
  • Novel stroke model for neuroprotective research: bioreaction of primary brain cell aggregates.
    2007-2010, funded by FCT (PTDC/BIO/69407/2006)
  • Carbon monoxide as a neuroprotective agent against hypoxia-ischemia and reperfusion.
    2007-2010, funded by FCT, Portugal (PTDC/SAU-NEU/64327/2006)
  • Advanced Control of BHK Cultivation Processes Based on Intracellular Metabolic Fluxes.
    2005-2007, funded by FCT, Portugal (POCI/BIO/57927/2004)
  • THERAVECT – Production, Purification and Storage of Retroviral Vectors Produced by Modular Master Producer Cells.
    2005-2007, funded by FCT, Portugal (010.6/A003/2005)
  • CELL CRYOTHERA – Cell Cryopreservation for Therapy and Regenerative Medicine.
    2005-2007, funded by FCT, Portugal (010.6/A006/2005)
  • Genetics, Stoicheometry and Kinetics of Multiple Protein Assembly: the case for a Rotavirus Like Particle.
    2005-2007, funded by FCT (POCTI/BIO/55975/2004)
  • Integrated strategy for the production, purification and storage of adenovirus.
    2004-2006, funded by FCT, Portugal (POCTI/BIO/46515/2002)
  • Metabolic Trafficking between neurons and astrocytes under stress conditions implicated in neurological disorders.
    2003-2006, funded by FCT, Portugal (POCTI/BIO/39214/2001)
  • Stabilization of retroviruses for gene therapy clinical applications.
    2001-2003, funded by FCT, Portugal (POCTI/BIO/35695/2000)
  • Cell cycle control for better biotechnological methods in therapeutic protein production.
    2001-2003, funded by FCT, Portugal (POCTI/BIO/35687/2000)