Publications

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Bioengineering for Cell-based Therapies
Process engineering of human pluripotent stem cells for clinical application
Trends in Biotechnology
Serra M, Brito C, Correia C, Alves PM
2012
Advanced Technologies for Gene Therapy Products
Integrated Strategy for the Production of Therapeutic Retroviral Vectors
Human Gene Therapy
Carrondo, Manuel and Panet, Amos and Wirth, Dagmar and Coroadinha, Ana Sofia and Cruz, Pedro and Falk, Haya and Schucht, Roland and Dupont, Francis and Geny-Fiamma, Cécile and Merten, Otto-Wilhelm and Hauser, Hansjörg
2011
Vaccines Bioprocess Engineering
Large-scale production and purification of VLP-based vaccines
Journal of Invertebrate Pathology
Vicente T, Roldão A, Peixoto C, Carrondo MJT, Alves PM
2011
Advanced Technologies for Gene Therapy Products
Improvement of lentiviral transfer vectors using cis-acting regulatory elements for increased gene expression
Applied Microbiology and Biotechnology
Real, Gonçalo, and Monteiro, Francisca and Burger, Christa and Alves, Paula M.
2011
Advanced Technologies for Gene Therapy Products
Manufacturing of Retroviruses
Humana Press
Cruz, P. E.; Rodrigues, T.; Carmo, M.; Wirth, D.; Amaral, A. I.; Alves, P. M.; Coroadinha, A. S.
2011
Modeling electrostatic interactions of baculovirus vectors for ion-exchange process development
Journal of Chromatography A
Vicente, Tiago and Peixoto, Cristina and Alves, Paula M. and Carrondo, Manuel J.T.
2010
Modeling protein binding and elution over a chromatographic surface probed by surface plasmon resonance
Journal of Chromatography A
Vicente, Tiago and Mota, José P.B. and Peixoto, Cristina and Alves, Paula M. and Carrondo, Manuel J.T.
2010
Extending Hepatocyte Functionality for Drug-Testing Applications Using High-Viscosity Alginate–Encapsulated Three-Dimensional Cultures in Bioreactors
Tissue Engineering Part C: Methods
Miranda, Joana P. and Rodrigues, Armanda and Tostões, Rui M. and Leite, Sofia and Zimmerman, Heiko and Carrondo, Manuel J.T. and Alves, Paula M.
2010
An integrated analysis of enzyme activities, cofactor pools and metabolic fluxes in baculovirus-infected Spodoptera frugiperda Sf9 cells
Journal of Biotechnology
Bernal, Vicente and Monteiro, Francisca and Carinhas, Nuno and Ambrósio, Raquel and Alves, Paula M.
2010
Analysis of adsorption of a baculovirus bioreaction bulk on an ion-exchange surface by surface plasmon resonance
Journal of Biotechnology
Vicente, Tiago and Mota, José P.B. and Peixoto, Cristina and Alves, Paula M. and Carrondo, Manuel J.T.
2010
The effect of the cell death suppressor vMIA on the production of a recombinant protein in the adenovirus-293 expression system
Protein Expression and Purification
Vieira, Helena L.A. and Cunha, Liliana and Goldmacher, Victor S. and Alves, Paula M.
2009
Advanced Cell Models for Drug Discovery and Translational Research
Towards an Extended Functional HepatocyteIn VitroCulture
Tissue Engineering Part C: Methods
Miranda, Joana P. and Leite, Sofia B. and Muller-Vieira, Ursula and Rodrigues, Armanda and Carrondo, Manuel J.T. and Alves, Paula M.
2009
Cryopreservation of Adherent Cells: Strategies to Improve Cell Viability and Function After Thawing
Tissue Engineering Part C: Methods
Malpique, Rita and Ehrhart, Friederike and Katsen-Globa, Alisa and Zimmermann, Heiko and Alves, Paula M.
2009
Thermosensitivity of the Reverse Transcription Process as an Inactivation Mechanism of Lentiviral Vectors
Human Gene Therapy
Carmo, M. and Dias, J.D. and Panet, A. and Coroadinha, A.S. and Carrondo, M.J.T. and Alves, P.M. and Cruz, P.E.
2009
Anti‐inflammatory effect of Rosmarinic acid on a model of carrageenan‐induced paw edema
The FASEB Journal
Rocha, João Pedro and Sepodes, Bruno Miguel and Eduardo‐Figueira, Maria and Bronze, Rosário and Duarte, Catarina and Serra, Teresa and Silva‐Lima, Beatriz and Mota‐Filipe, Helder
2009
Stirred bioreactors for the expansion of adult pancreatic stem cells
Annals of Anatomy - Anatomischer Anzeiger
Serra, Margarida and Brito, Catarina and Leite, Sofia B. and Gorjup, Erwin and von Briesen, Hagen and Carrondo, Manuel J.T. and Alves, Paula M.
2009
Vaccines Bioprocess Engineering
Scalable culture systems using different cell lines for the production of Peste des Petits ruminants vaccine
Vaccine
Silva, Ana Carina and Delgado, Inês and Sousa, Marcos F.Q. and Carrondo, Manuel J.T. and Alves, Paula M.
2008
Sodium dodecyl sulfate-capillary gel electrophoresis analysis of rotavirus-like particles
Journal of Chromatography A
Mellado, Maria Candida M. and Franco, Catarina and Coelho, Ana and Alves, Paula M. and Simplício, Ana Luísa
2008
Advanced Technologies for Gene Therapy Products
From retroviral vector production to gene transfer: spontaneous inactivation is caused by loss of reverse transcription capacity
The Journal of Gene Medicine
Carmo, M. and Panet, A. and Carrondo, M. J. T. and Alves, P. M. and Cruz, P. E.
2008