Publications

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Natural Bioactives & Nutraceuticals
Antibacterial and Antifungal Activity of Extracts from Five Portuguese Cowpea (Vigna unguiculata) Accessions
Molecules
Salamandane A, Candeias M, Lourenço S, Vieira EJF, Mecha E, Gomes R, Bronze R, Nunes C, Brito L
2025
Bioanalytics
Multispecific antibodies: Bioanalytics for early-stage screening and characterization of mispairing profiles
PLOS One
Melo C, Carvalho SB, Sebastião MJ, Gomes RA, Sousa PMF, Gomes-Alves P
2025
Advanced Cell Models for Drug Discovery and Translational Research
3D co-cultures of primary human hepatocytes and Kupffer-like cells to address innate immune responses to rAAV
Scientific Reports
Ramella Gal I, Arez F, Correia IP, Domenici G, Fernandes S, Silva G, Saldanha I, Duarte N, Freitas C, Alves PM, Maier U, Coroadinha AS, du Plessis F, Brito C
2025
Bioengineering for Cell-based Therapies
Billion‐Scale Expansion of Functional hiPSC‐Derived Cardiomyocytes in Bioreactors Through Oxygen Control and Continuous Wnt Activation
Advanced Science
Vicente P, Inocêncio LR, Ullate‐Agote A, Louro AF, Jacinto J, Gamelas B, Iglesias‐García O, Martin‐Uriz PS, Aguirre‐Ruiz P, Ríos‐Muñoz GR, Fernández‐Santos ME, van Mil A, Sluijter JPG, Prósper F, Mazo MMV, Alves PM, Serra M
2025
Advanced Cell Models for Drug Discovery and Translational Research
Sustained Macrophage Reprogramming Is Required for CD8+ T cell–Dependent Long-Term Tumor Eradication
Cancer Immunology Research
Jardim C, Bica M, Reis-Sobreiro M, Teixeira da Mota A, Lopes R, Pinto MF, Sousa NS, Mensurado S, Boekhoff H, Scolaro T, Reugebrink M, Goncalves-Sousa N, Kubo H, Gomes CM, Brito C, Argüello RJ, Leites EP, Morais VA, Silva-Santos B, Barbosa-Morais NL, Serre K
2025
Vaccines Bioprocess Engineering
Site-directed tyrosinase conjugation on engineered ferritin retains immune recognition
Scientific Reports
Rodrigues MQ, Thomaz M, Gomes RA, Alves PM, Roldão A
2025
Advanced Technologies for Gene Therapy Products
SLC20A1 knockout to stably express a fusogenic gibbon ape leukemia virus envelope glycoprotein for lentiviral vector production
Molecular Therapy Methods & Clinical Development
Nogueira RJ, Rodrigues AF, Mestre DA, Coroadinha AS
2025
Bioengineering for Cell-based Therapies
Heterotypic spheroids as a strategy for 3D culture of cryopreserved primary human hepatocytes in stirred-tank systems
SLAS Discovery
Arez F, Preiss L, Ramella Gal I, Rebelo SP, Badolo L, Brito C, Spangenberg T, Alves PM
2025
Microbiology and Molecular Biology
Wastewater Metavirome Diversity: Exploring Replicate Inconsistencies and Bioinformatic Tool Disparities
International Journal of Environmental Research and Public Health
Santos AFB, Nunes M, Filipa-Silva A, Pimentel V, Pingarilho M, Abrantes P, Miranda MNS, Crespo MTB, Abecasis AB, Parreira R, Seabra SG
2025
Advanced Cell Models for Drug Discovery and Translational Research
Engineering a Perfusion Bioreactor System for hiPSC‐Derived Progenitor Co‐Culture Capturing Microglial Features in CNS Development
Biotechnology and Bioengineering
Gomes CM, de Sá I, Delgado M, Alves PM, Brito C
2025
Protein Biophysics for Drug Discovery
Phenotypic Hit Identification and Optimization of Novel Pan-TEAD and Subtype-Selective Inhibitors
Journal of Medicinal Chemistry
Heinrich T, Gambardella A, Schwarz D, Petersson C, Gunera J, Garg S, Schneider R, Keil M, Grimmeisen L, Unzue Lopez A, Schilke H, Weitzel T, Kolb C, Diehl P, Doerfel B, Anlauf U, Reither V, Rettig C, Opelt B, Delp A, Wildner N, Musil D, Friedrich E, Burgdorf L, Fuchss T, Albers L, Sousa PMF, Freire F, Bandeiras TM, Wienke D.
2025
Natural Bioactives & Nutraceuticals
Matching the Sensory Analysis of Serpa PDO Cheese with the Volatile Profiles—A Preliminary Study
Foods
Macedo A, Carvalho MJ, Mecha E, Costa L, Ferreira A, Inácio RS, Bronze MDR
2025
Natural Bioactives & Nutraceuticals
Impact of low-moisture extrusion on carbohydrate constituents and antinutrients of a blend of a faba bean protein concentrate and a beta-glucan enriched oat fraction
Food Research International
Saldanha do Carmo C, Mecha E, Schmidt G, Oliveira J, Bronze MR, Knutsen SH, Serra AT
2025
Protein Biophysics for Drug Discovery
Pushing the limits of hydrogen/deuterium exchange mass spectrometry to study protein:fragment low affinity interactions
Communications Chemistry
Malta CF, Silva DO, Grädler U, Sousa PMF, Musil D, Schwarz D, Bomke J, Bandeiras TM, Bortoluzzi A
2025
Advanced Technologies for Gene Therapy Products
Purification of AAV8 through a scalable two-step monolithic chromatography approach
Journal of Chromatography A
Nascimento A, Faria TQ, Bollmann F, Noverraz M, Pressac G, Roldão A, Peixoto C, Silva RJS
2025
Vaccines Bioprocess Engineering
Engineered thermoswitch in the baculovirus expression vector system for production of virus-like particle vaccines with minimized baculovirus contaminants
Trends in Biotechnology
van Oosten L, Altenburg JJ, Nowee G, Kenbeek D, Neef T, Rouw T, Tegelbeckers VIP, van der Heijden J, Mentink S, Willemsen W, Hausjell CS, Kuijpers L, van der Pol L, Roldão A, Correia R, van den Born E, Wijffels RH, Martens DE, van Oers MM, Pijlman GP
2025
Microbiology and Molecular Biology
Treatment of wastewater effluents using nanofiltration and low pressure UV photolysis to produce high quality water for food production
Water Research
Cristóvão MB, Sério J, Marques AP, Bento-Silva A, Gossard M, Vergara-Diaz O, Silva AF, Nunes M, Bronze MR, de Oliveira PB, Crespo MTB, Crespo JG, Pereira VJ
2025
Streamlining the purification of a clinical-grade oncolytic virus for therapeutic applications
Separation and Purification Technology
Fernandes RP, Göbel S, Reiter M, Bryan A, Altomonte J, Genzel Y, Peixoto C
2025
Microbiology and Molecular Biology
Integration of spectroscopic techniques and machine learning for optimizing Phaeodactylum tricornutum cell and fucoxanthin productivity
Bioresource Technology
Reynolds-Brandão P, Quintas-Nunes F, Bertrand CF, Martins RM, Crespo MTB, Galinha CF, Nascimento FX
2025
Microbiology and Molecular Biology
From Dormancy to Eradication: Strategies for Controlling Bacterial Persisters in Food Settings
Foods
Serrano S, Grujović MŽ, Marković KG, Barreto-Crespo MT, Semedo-Lemsaddek T
2025
Vaccines Bioprocess Engineering
Virus-like particle vaccine with authentic quaternary epitopes protects against Zika virus-induced viremia and testicular damage
Journal of Virology
Abbo SR, Yan K, Geertsema C, Hick TAH, Altenburg JJ, Nowee G, van Toor C, van Lent JW, Nakayama E, Tang B, Metz SW, Bhowmik R, de Silva AM, Prow NA, Correia R, Alves PM, Roldão A, Martens DE, van Oers MM, Suhrbier A, Pijlman GP
2025
Protein Biophysics for Drug Discovery
Fragment-Based Discovery and Structure-Led Optimization of MSC778, the First Potent, Selective, and Orally Bioavailable FEN1 Inhibitor
Journal of Medicinal Chemistry
Mann SE, Lefranc J, Alkhatib O, Boivin R, Bomke J, Byrne RT, Cassona CP, Chen X, Cornaciu I, Costales P, Davis OA, DeSelm L, Elinati E, Follows B, Galbiati A, Göldner C, Hayre JK, Jorand-Lebrun C, Lademann CA, Leuthner B, Majithiya JB, Malta CF, Mason B, McWhirter CL, Neff B, Nissink JWM, Pehl U, Petersson C, Pica A, Pinto MF, Rajendra E, Rakers C, Toste Rêgo A, Robinson HMR, Sala-Hojman A, Schaedler TA, Schürmann PJL, Silva DO, Smith GCM, Sorrell F, Webster GR, Zenke FT, Heald RA, Burgdorf LT
2025
Microbiology and Molecular Biology
Beyond guaiacol and halophenols: Unravelling isobutyric and isovaleric acids as new culprits in off-flavour spoilage by Alicyclobacillus spp.
International Journal of Food Microbiology
Leonardo IC, Ferreira A, Bronze MR, Quendera AP, Fernandes AF, Barreto Crespo MT, Bustos Gaspar F
2025
Bioengineering for Cell-based Therapies
Controlled activation modulates T-cell expansion and phenotype in stirred-tank bioreactors
Cytotherapy
Costa MS, Costa CM, Matos LN, Sebastião MJ, Duarte N, Costa MHG, Serra M
2025