Publications

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Bioengineering for Cell-based Therapies
Enhanced bioprocess control to advance the manufacture of mesenchymal stromal cell‐derived extracellular vesicles in stirred‐tank bioreactors
Biotechnology and Bioengineering
Costa, Marta H. G. and Costa, Margarida S. and Painho, Beatriz and Sousa, Carolina D. and Carrondo, Inês and Oltra, Enrique and Pelacho, Beatriz and Prosper, Felipe and Isidro, Inês A. and Alves, Paula and Serra, Margarida
2023
Advanced Technologies for Gene Therapy Products
Efficient adeno-associated virus serotype 5 capture with affinity functionalized nanofiber adsorbents
Frontiers in Bioengineering and Biotechnology
S Neto, J P Mendes, S B Dos Santos, A Solbrand, M J T Carrondo, C Peixoto, R J S Silva
2023
Advanced Technologies for Gene Therapy Products
Implementation of Novel Affinity Ligand for Lentiviral Vector Purification
International Journal of Molecular Sciences
Moreira, Ana Sofia and Bezemer, Sandra and Faria, Tiago Q. and Detmers, Frank and Hermans, Pim and Sierkstra, Laurens and Coroadinha, Ana Sofia and Peixoto, Cristina
2023
Natural Bioactives & Nutraceuticals
Green Processing of Black Raspberry Pomace: Application of Sonotrode-Based Extraction Technique and Particles from Gas-Saturated Solutions (PGSS) Technology
Foods
Nastić, N.; Mutavski, Z.; Živković, J.; Ambrus, R.; Fernández, N.; Menković, N.; Vidović, S.
2023
Advanced Technologies for Gene Therapy Products
Towards a scalable bioprocess for rAAV production using a HeLa stable cell line
Biotechnology and Bioengineering
J Escandell, F Moura, S B Carvalho, R J S Silva, R Correia, A Roldão, P Gomes-Alves, P M Alves
2023
Natural Bioactives & Nutraceuticals
Isolation of bluish anthocyanin-derived pigments obtained from blueberry surplus using centrifugal partition chromatography
Journal of Chromatography
A N Nunes, V Ivasiv, L F Gouveia, N Fernandez, J Oliveira, M R Bronze, A A Matias
2023
Advanced Technologies for Gene Therapy Products
Extending AAV Packaging Cargo through Dual Co-Transduction: Efficient Protein Trans-Splicing at Low Vector Doses
International Journal of Molecular Sciences
Ferreira, Mariana V. and Fernandes, Sofia and Almeida, Ana Isabel and Neto, Salomé and Mendes, João P. and Silva, Ricardo J. S. and Peixoto, Cristina and Coroadinha, Ana Sofia
2023
Bioengineering for Cell-based Therapies
Transcriptome and proteome profiling of activated cardiac fibroblasts supports target prioritization in cardiac fibrosis
Frontiers in Cardiovascular Medicine
Moita, M. R.; Silva, M. M.; Diniz, C.; Serra, M.; Hoet, R. M.; Barbas, A.; Simão, D.
2022
Bioengineering for Cell-based Therapies
Bioactivity and miRNome Profiling of Native Extracellular Vesicles in Human Induced Pluripotent Stem Cell-Cardiomyocyte Differentiation.
Advanced Sciences
Louro AF, Paiva MA, Oliveira MR, Kasper KA, Alves PM, Gomes-Alves P, Serra M
2022
Vaccines Bioprocess Engineering
Asexual blood-stage malaria vaccine candidate PfRipr5: enhanced production in insect cells
Frontiers in Bioengineering and Biotechnology
R Correia, B Fernandes, R Castro, H Nagaoka, E Takashima, T Tsuboi, A Fukushima, NK Viebig, H Depraetere, PM Alves, A Roldao
2022
Vaccines Bioprocess Engineering
Integrating high cell density cultures with adapted laboratory evolution for improved Gag-HA virus-like particles production in stable insect cell lines
Biotechnology and Bioengineering
B Fernandes, R Correia, M Sousa, MJT Carrondo, PM Alves, A Roldão
2022
Natural Bioactives & Nutraceuticals
Comprehensive Two-Dimensional Gas Chromatography as a Powerful Strategy for the Exploration of Broas Volatile Composition
Molecules
A Bento-Silva, N Duarte, M Santos, C P Costa, M C Vaz Patto, S M Rocha, M R Bronze
2022
Natural Bioactives & Nutraceuticals
Saffron against Neuro-Cognitive Disorders: An Overview of Its Main Bioactive Compounds, Their Metabolic Fate and Potential Mechanisms of Neurological Protection
Nutrients
D Cerdá-Bernad, L Costa, A T Serra, M R Bronze, E Valero-Cases, F Pérez-Llamas, M E Candela, M B. Arnao, F T Barberán, R G Villalba, MT García-Conesa, M J Frutos
2022
Advanced Technologies for Gene Therapy Products
Continuous Affinity Purification of Adeno-Associated Virus Using Periodic Counter-Current Chromatography
Pharmaceutics
J P Mendes,M Bergman,A Solbrand,C Peixoto, M J T Carrondo, R J S Silva
2022
Vaccines Bioprocess Engineering
Development of versatile affinity-based system for one step purification process: Case of Group A Streptococcus vaccine
Biotechnology and Bioengineering
A Chevrel, L Candela, E Innocenti, C Golibrzuch, R Skudas, A Schwämmle, M J T Carrondo, O Kitten, M Nissum, R J S Silva
2022
Protein Biophysics for Drug Discovery
Optimization of TEAD P-Site Binding Fragment Hit into In Vivo Active Lead MSC-4106
J Med Chem
T Heinrich, C Peterson, R Schneider, S Garg, D Schwarz, J Gunera, A Seshire, L Kötzner, S Schlesiger, D Musil, H Schilke, B Doerfel, P Diehl, P Böpple, AR Lemos, PMF Sousa, F Freire, TM Bandeiras, E Carswell, N Pearson, S Sirohi, M Hooker, E Trivier, R Broome, A Balsiger, A Crowden, C Dillon, and D Wienke
2022
Advanced Technologies for Gene Therapy Products
AAV process intensification by perfusion bioreaction and integrated clarification
 Frontiers in Bioengineering and Biotechnology
João P. Mendes, B Fernandes, E Pineda, S Kudugunti, M Bransby, R Gantier, C Peixoto, P M Alves, A Roldão, R J S Silva
2022
Bioengineering for Cell-based Therapies
Expression of Extracellular Vesicle PIWI-Interacting RNAs Throughout hiPSC-Cardiomyocyte Differentiation
Frontiers in Physiology
Louro, A. F.; Virgolini, N.; Paiva, M. A.; Isidro, I. A.; Alves, P. M.; Gomes-Alves, P.; Serra, M.
2022
Advanced Cell Models for Drug Discovery and Translational Research
Capturing the third dimension in drug discovery: spatially resolved tools for interrogation of complex 3D cell models
Biotechnology Advances
D Simão, C M Gomes, P M Alves, C Brito
2022
Vaccines Bioprocess Engineering
Intensifying Continuous Production of Gag-HA VLPs at High Cell Density Using Stable Insect Cells Adapted to Low Culture Temperature
Frontiers in Bioengineering and Biotechnology
Fernandes, B.; Correia, R.; Alves, P. M.; Roldão, A.
2022
Microbiology and Molecular Biology
Unveiling the complete genome sequence of Alicyclobacillus acidoterrestris DSM 3922T, a taint-producing strain.
G3
I C Leonardo, M T Barreto Crespo, F B Gaspar
2022
Microbiology and Molecular Biology
Nanofiltration as an Efficient Tertiary Wastewater Treatment: Elimination of Total Bacteria and Antibiotic Resistance Genes from the Discharged Effluent of a Full-Scale Wastewater Treatment Plant.
Antibiotics
M Oliveira, I C Leonardo, A F Silva, J Goulão Crespo, M Nunes, M T Barreto Crespo
2022
Natural Bioactives & Nutraceuticals
Single Dose of Marine Chlorella vulgaris Increases Plasma Concentrations of Lutein, β-Carotene and Zeaxanthin in Healthy Male Volunteers
Antioxidants
A T Serra, S D Silva, L Pleno de Gouveia, A M R C Alexandre, C V Pereira, A B Pereira, A C Partidário, N E Silva, T Bohn, V S S Gonçalves, G Real, P Escudero, N Fernández, A A Matias, M R Bronze
2021
Advanced Technologies for Gene Therapy Products
Progress and Perspectives in the Development of Lentiviral Vector Producer Cells
Biotechnology Journal
M V Ferreira, E T Cabral, A S Coroadinha
2021