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Vaccines Bioprocess Engineering
Potential business model for a European vaccine R&D infrastructure and its estimated socio-economic impact
F1000Research
Jungbluth S, Martin W, Slezak M, Depraetere H, Guzman CA, Ussi A, Morrow D, Van Heuverswyn F, Arnouts S, Carrondo MJT, Olesen O, Ottenhoff THM, Dockrell HM, Ho MM, Dobly A, Christensen D, Segalés J, Laurent F, Lantier F, Stockhofe‑Zurwieden N, Morelli F, Langermans JAM, Verreck FAW, Le Grand R, Sloots A, Medaglini D, Lawrenz M, Collin N
2023
Vaccines Bioprocess Engineering
Impact of dual‐baculovirus infection on the Sf9 insect cell transcriptome during rAAV production using single‐cell RNA‐seq
Biotechnology and Bioengineering
Virgolini N, Silvano M, Hagan R, Correia R, Alves PM, Clarke C, Roldão A, Isidro IA
2023
Natural Bioactives & Nutraceuticals
Isolation of bluish anthocyanin-derived pigments obtained from blueberry surplus using centrifugal partition chromatography
Journal of Chromatography
Nunes AN, Ivasiv V, Gouveia LF, Fernandez N, Oliveira J, Bronze MR, Matias AA
2023
Natural Bioactives & Nutraceuticals
Lactucin Synthase Inactivation Boosts the Accumulation of Anti-inflammatory 8-Deoxylactucin and Its Derivatives in Chicory (Cichorium intybus L.)
Journal of Agricultural and Food Chemistry
Cankar K, Hakkert JC, Sevenier R, Papastolopoulou C, Schipper B, Baixinho JP, Fernández N, Matos MS, Serra AT, Santos CN, Vahabi K, Tissier A, Bundock P, Bosch D
2023
Advanced Technologies for Gene Therapy Products
Efficient adeno-associated virus serotype 5 capture with affinity functionalized nanofiber adsorbents
Frontiers in Bioengineering and Biotechnology
Neto S, Mendes JP, Dos Santos SB, Solbrand A, Carrondo MJT, Peixoto C, Silva RJS
2023
Vaccines Bioprocess Engineering
Humoral and T cell responses to SARS-CoV-2 reveal insights into immunity during the early pandemic period in Pakistan
BMC Infectious Diseases
Masood KI, Qaiser S, Abidi SH, Khan E, Mahmood SF, Hussain A, Ghous Z, Imtiaz K, Ali N, Hasan M, Memon HA, Yameen M, Ali S, Baloch S, Lakhani G, Alves PM, Iqbal NT, Ahmed K, Iqbal J, Bhutta ZA, Hussain R, Rottenberg M, Simas JP, Veldhoen M, Ghias K, Hasan Z
2023
Microbiology and Molecular Biology
Plant Growth Promotion, Phytohormone Production and Genomics of the Rhizosphere-Associated Microalga, Micractinium rhizosphaerae sp. nov.
Plants
Quintas-Nunes F, Brandão PR, Crespo MTB, Glick BR, Nascimento FX
2023
Natural Bioactives & Nutraceuticals
High Inter- and Intra- Diversity of Amino Acid Content and Protein Digestibility Disclosed in Five Cool Season Legume Species with a Growing Market Demand
Foods
Mecha E, Alves ML, Bento da Silva A, Pereira AB, Rubiales D, Vaz Patto MC, Bronze MR
2023
Advanced Technologies for Gene Therapy Products
Implementation of Novel Affinity Ligand for Lentiviral Vector Purification
International Journal of Molecular Sciences
Moreira AS, Bezemer S, Faria TQ, Detmers F, Hermans P, Sierkstra L, Coroadinha AS, Peixoto C
2023
Bioengineering for Cell-based Therapies
Microfiber-reinforced hydrogels prolong the release of human induced pluripotent stem cell-derived extracellular vesicles to promote endothelial migration
Biomaterials Advances
Cedillo-Servin G, Louro AF, Gamelas B, Meliciano A, Zijl A, Alves PM, Malda J, Serra M, Castilho M
2023
Bioengineering for Cell-based Therapies
Advanced cell technologies: Making protein, cell, and gene therapies a reality
Biotechnology and Bioengineering
Geada, Isabelle and Roldão, Antonio and Betenbaugh, Michael J. and Alves, Paula M.
2023
Natural Bioactives & Nutraceuticals
Arabinoxylan from Corn Fiber Obtained through Alkaline Extraction and Membrane Purification: Relating Bioactivities with the Phenolic Compounds
Molecules
Weng V, Cardeira M, Bento‑Silva A, Serra AT, Brazinha C, Bronze MR
2023
Microbiology and Molecular Biology
Nanofiltration combined with ozone-based processes for the removal of antineoplastic drugs from wastewater effluents
Journal of Environmental Management
Gouveia TIA, Gorito AM, Cristóvão MB, Pereira VJ, Crespo JG, Alves A, Pereira MFR, Ribeiro ARL, Silva AMT, Santos MSF
2023
Advanced Cell Models for Drug Discovery and Translational Research
Tackling the tumor microenvironment – how can complex tumor models in vitro aid oncology drug development?
Expert Opinion on Drug Discovery
Cox MC, Mendes R, Halwachs KN, Domenici G, Brito C, Boghaert ER
2023
Natural Bioactives & Nutraceuticals
Selenium Bio-Nanocomposite Based on Alteromonas macleodii Mo169 Exopolysaccharide: Synthesis, Characterization, and In Vitro Antioxidant Activity
Bioengineering
Concórdio‑Reis P, Macedo AC, Cardeira M, Moppert X, Guézennec J, Sevrin C, Grandfils C, Serra AT, Freitas F
2023
Protein Biophysics for Drug Discovery
Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding
Journal of Biological Chemistry
Grädler U, Schwarz D, Wegener A, Eichhorn T, Bandeiras TM, Freitas MC, Lammens A, Ganichkin O, Augustin M, Minguzzi S, Becker F, Bomke J
2023
Advanced Technologies for Gene Therapy Products
Exploring nutrient supplementation and bioprocess optimization to improve the production of lentiviral vectors in serum‐free medium suspension cultures
Biotechnology Journal
Vaz TA, Rodrigues AF, Coroadinha AS
2023
Natural Bioactives & Nutraceuticals
Comprehensive Two-Dimensional Gas Chromatography as a Powerful Strategy for the Exploration of Broas Volatile Composition
Molecules
A Bento-Silva, N Duarte, M Santos, C P Costa, M C Vaz Patto, S M Rocha, M R Bronze
2022
Vaccines Bioprocess Engineering
A novel asexual blood-stage malaria vaccine candidate: PfRipr5 formulated with human-use adjuvants induces potent growth inhibitory antibodies
Frontiers in Immunology
Takashima E, Nagaoka H, Correia R, Alves PM, Roldão A, Christensen D, Guderian JA, Fukushima A, Viebig NK, Depraetere H, Tsuboi T
2022
Advanced Technologies for Gene Therapy Products
Leveraging rAAV bioprocess understanding and next generation bioanalytics development
Current Opinion in Biotechnology
Escandell JM, Pais D Am, Carvalho SB, Vincent K, Gomes‑Alves P, Alves PM
2022
Transcriptome analysis of Sf9 insect cells during production of recombinant Adeno‐associated virus
Biotechnology Journal
Virgolini N, Hagan R, Correia R, Silvano M, Fernandes S, Alves PM, Clarke C, Roldão A, Isidro IA
2022
Natural Bioactives & Nutraceuticals
Saffron against Neuro-Cognitive Disorders: An Overview of Its Main Bioactive Compounds, Their Metabolic Fate and Potential Mechanisms of Neurological Protection
Nutrients
D Cerdá-Bernad, L Costa, A T Serra, M R Bronze, E Valero-Cases, F Pérez-Llamas, M E Candela, M B. Arnao, F T Barberán, R G Villalba, MT García-Conesa, M J Frutos
2022
Protein Biophysics for Drug Discovery
Deciphering cellular and molecular determinants of human DPCD protein in complex with RUVBL1/RUVBL2 AAA-ATPases
Journal of Molecular Biology
Dos Santos Morais R, Santo PE, Ley M, Schelcher C, Abel Y, Plassart L, Deslignière E, Chagot ME, Quinternet M, Paiva ACF, Hessmann S, Morellet N, M F Sousa P, Vandermoere F, Bertrand E, Charpentier B, Bandeiras TM, Plisson-Chastang C, Verheggen C, Cianférani S, Manival X
2022
Advanced Technologies for Gene Therapy Products
Continuous Affinity Purification of Adeno-Associated Virus Using Periodic Counter-Current Chromatography
Pharmaceutics
J P Mendes,M Bergman,A Solbrand,C Peixoto, M J T Carrondo, R J S Silva
2022