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Advanced Cell Models for Drug Discovery and Translational Research
Modeling Human Neural FunctionalityIn Vitro: Three-Dimensional Culture for Dopaminergic Differentiation
Tissue Engineering Part A
Simão, D.; Pinto, C.; Piersanti, S.; Weston, A.; Peddie, C. J.; Bastos, A. E. P.; Licursi, V.; Schwarz, S. C.; Collinson, L. M.; Salinas, S.; Serra, M.; Teixeira, A. P.; Saggio, I.; Lima, P. A.; Kremer, E. J.; Schiavo, G.; Brito, C.; Alves, P. M.
2015
Natural Bioactives & Nutraceuticals
Production of a natural red pigment derived from Opuntia spp. using a novel high pressure CO2assisted-process
RSC Advances
Nunes, A. N.; Saldanha do Carmo, C.; Duarte, C. M. M.
2015
Natural Bioactives & Nutraceuticals
Impact of a 6-wk olive oil supplementation in healthy adults on urinary proteomic biomarkers of coronary artery disease, chronic kidney disease, and diabetes (types 1 and 2): a randomized, parallel, controlled, double-blind study
American Journal of Clinical Nutrition
S Silva, M R Bronze, M E Figueira, J Siwy, H Mischak, E Combet, W Mullen
2015
Bioengineering for Cell-based Therapies
Robust Expansion of Human Pluripotent Stem Cells: Integration of Bioprocess Design With Transcriptomic and Metabolomic Characterization
Stem Cells Translational Medicine
Silva, M. M.; Rodrigues, A. F.; Correia, C.; Sousa, M. F. Q.; Brito, C.; Coroadinha, A. S.; Serra, M.; Alves, P. M.
2015
Bioengineering for Cell-based Therapies
Production of oncolytic adenovirus and human mesenchymal stem cells in a single‐use, Vertical‐Wheel bioreactor system: Impact of bioreactor design on performance of microcarrier‐based cell culture processes
Biotechnology Progress
Sousa, M. F. Q.; Silva, M. M.; Giroux, D.; Hashimura, Y.; Wesselschmidt, R.; Lee, B.; Roldão, A.; Carrondo, M. J. T.; Alves, P. M.; Serra, M.
2015
Natural Bioactives & Nutraceuticals
Chemical characterization of a red raspberry fruit extract and evaluation of its pharmacological effects in experimental models of acute inflammation and collagen-induced arthritis
Food Funct.
Figueira, M. E.; Câmara, M. B.; Direito, R.; Rocha, J.; Serra, A. T.; Duarte, C. M. M.; Fernandes, A.; Freitas, M.; Fernandes, E.; Marques, M. C.; Bronze, M. R.; Sepodes, B.
2014
Natural Bioactives & Nutraceuticals
Anti‐inflammatory Effect of Rosmarinic Acid and an Extract of Rosmarinus officinalis in Rat Models of Local and Systemic Inflammation
Basic & Clinical Pharmacology & Toxicology
Rocha, J.; Eduardo‐Figueira, M.; Barateiro, A.; Fernandes, A.; Brites, D.; Bronze, R.; Duarte, C. M. M.; Serra, A. T.; Pinto, R.; Freitas, M.; Fernandes, E.; Silva‐Lima, B.; Mota‐Filipe, H.; Sepodes, B.
2014
Bioengineering for Cell-based Therapies
Metabolic responses of CHO cells to limitation of key amino acids
Biotechnology and Bioengineering
Duarte, T. M.; Carinhas, N.; Barreiro, L. C.; Carrondo, M. J. T.; Alves, P. M.; Teixeira, A. P.
2014
Microbiology and Molecular Biology
Annual ryegrass-associated bacteria with potential for plant growth promotion
Microbiological Research
Castanheira, N.; Dourado, A. C.; Alves, P. I.; Cortés-Pallero, A. M.; Delgado-Rodríguez, A. I.; Prazeres, Â.; Borges, N.; Sánchez, C.; Barreto Crespo, M. T.; Fareleira, P.
2014
Bioengineering for Cell-based Therapies
Process engineering of human pluripotent stem cells for clinical application
Trends in Biotechnology
Serra M, Brito C, Correia C, Alves PM
2012
Advanced Technologies for Gene Therapy Products
Improvement of lentiviral transfer vectors using cis-acting regulatory elements for increased gene expression
Applied Microbiology and Biotechnology
Real, Gonçalo, and Monteiro, Francisca and Burger, Christa and Alves, Paula M.
2011
Advanced Technologies for Gene Therapy Products
Manufacturing of Retroviruses
Humana Press
Cruz, P. E.; Rodrigues, T.; Carmo, M.; Wirth, D.; Amaral, A. I.; Alves, P. M.; Coroadinha, A. S.
2011
Advanced Technologies for Gene Therapy Products
Integrated Strategy for the Production of Therapeutic Retroviral Vectors
Human Gene Therapy
Carrondo, Manuel and Panet, Amos and Wirth, Dagmar and Coroadinha, Ana Sofia and Cruz, Pedro and Falk, Haya and Schucht, Roland and Dupont, Francis and Geny-Fiamma, Cécile and Merten, Otto-Wilhelm and Hauser, Hansjörg
2011
Analysis of adsorption of a baculovirus bioreaction bulk on an ion-exchange surface by surface plasmon resonance
Journal of Biotechnology
Vicente, Tiago and Mota, José P.B. and Peixoto, Cristina and Alves, Paula M. and Carrondo, Manuel J.T.
2010
Modeling electrostatic interactions of baculovirus vectors for ion-exchange process development
Journal of Chromatography A
Vicente, Tiago and Peixoto, Cristina and Alves, Paula M. and Carrondo, Manuel J.T.
2010
Modeling protein binding and elution over a chromatographic surface probed by surface plasmon resonance
Journal of Chromatography A
Vicente, Tiago and Mota, José P.B. and Peixoto, Cristina and Alves, Paula M. and Carrondo, Manuel J.T.
2010
An integrated analysis of enzyme activities, cofactor pools and metabolic fluxes in baculovirus-infected Spodoptera frugiperda Sf9 cells
Journal of Biotechnology
Bernal, Vicente and Monteiro, Francisca and Carinhas, Nuno and Ambrósio, Raquel and Alves, Paula M.
2010
Extending Hepatocyte Functionality for Drug-Testing Applications Using High-Viscosity Alginate–Encapsulated Three-Dimensional Cultures in Bioreactors
Tissue Engineering Part C: Methods
Miranda, Joana P. and Rodrigues, Armanda and Tostões, Rui M. and Leite, Sofia and Zimmerman, Heiko and Carrondo, Manuel J.T. and Alves, Paula M.
2010
Cryopreservation of Adherent Cells: Strategies to Improve Cell Viability and Function After Thawing
Tissue Engineering Part C: Methods
Malpique, Rita and Ehrhart, Friederike and Katsen-Globa, Alisa and Zimmermann, Heiko and Alves, Paula M.
2009
Anti‐inflammatory effect of Rosmarinic acid on a model of carrageenan‐induced paw edema
The FASEB Journal
Rocha, João Pedro and Sepodes, Bruno Miguel and Eduardo‐Figueira, Maria and Bronze, Rosário and Duarte, Catarina and Serra, Teresa and Silva‐Lima, Beatriz and Mota‐Filipe, Helder
2009
Advanced Cell Models for Drug Discovery and Translational Research
Towards an Extended Functional HepatocyteIn VitroCulture
Tissue Engineering Part C: Methods
Miranda, Joana P. and Leite, Sofia B. and Muller-Vieira, Ursula and Rodrigues, Armanda and Carrondo, Manuel J.T. and Alves, Paula M.
2009
Thermosensitivity of the Reverse Transcription Process as an Inactivation Mechanism of Lentiviral Vectors
Human Gene Therapy
Carmo, M. and Dias, J.D. and Panet, A. and Coroadinha, A.S. and Carrondo, M.J.T. and Alves, P.M. and Cruz, P.E.
2009
Stirred bioreactors for the expansion of adult pancreatic stem cells
Annals of Anatomy - Anatomischer Anzeiger
Serra, Margarida and Brito, Catarina and Leite, Sofia B. and Gorjup, Erwin and von Briesen, Hagen and Carrondo, Manuel J.T. and Alves, Paula M.
2009
The effect of the cell death suppressor vMIA on the production of a recombinant protein in the adenovirus-293 expression system
Protein Expression and Purification
Vieira, Helena L.A. and Cunha, Liliana and Goldmacher, Victor S. and Alves, Paula M.
2009