Publications

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Natural Bioactives & Nutraceuticals
Antiproliferative Effect of Colonic Fermented Phenolic Compounds from Jaboticaba (Myrciaria trunciflora) Fruit Peel in a 3D Cell Model of Colorectal Cancer
Molecules
Augusti PR, Quatrin A, Mello R, Bochi VC, Rodrigues E, Prazeres ID, Macedo AC, Oliveira-Alves SC, Emanuelli T, Bronze MR, Serra AT
2021
Bioengineering for Cell-based Therapies
Online monitoring of hiPSC expansion and hepatic differentiation in 3D culture by dielectric spectroscopy
Biotechnology and Bioengineering
Isidro AI, Vicente P, Pais DAM, Almeida JI, Domingues M, Abecasis B, Zapata-Linares L, Rodriguez-Madoz JR, Prosper F, Aspegren A, Alves PM, SERRA M
2021
Natural Bioactives & Nutraceuticals
Olive Pomace Phenolic Compounds Stability and Safety Evaluation: From Raw Material to Future Ophthalmic Applications
Molecules
Katsinas N, Enríquez-de-Salamanca A, Bento da Silva A, Bronze MR, Rodríguez-Rojo S
2021
Natural Bioactives & Nutraceuticals
Supercritical CO2 Extraction as a Tool to Isolate Anti-Inflammatory Sesquiterpene Lactones from Cichorium intybus L. Roots
Molecules
Baixinho JP, Anastácio JD, Ivasiv V, Cankar K, Bosch D, Menezes R, de Roode M, dos Santos CN, Matias AA, Fernández N
2021
Natural Bioactives & Nutraceuticals
Chicory Extracts and Sesquiterpene Lactones Show Potent Activity against Bacterial and Fungal Pathogens
Pharmaceuticals
Häkkinen ST, Soković M, Nohynek L, Ćirić A, Ivanov M, Stojković D, Tsitko I, Matos M, Baixinho JP, Ivasiv V, Fernández N, Nunes Dos Santos C, Oksman-Caldentey KM
2021
Advanced Technologies for Gene Therapy Products
Cell Bank Origin of MDCK Parental Cells Shapes Adaptation to Serum-Free Suspension Culture and Canine Adenoviral Vector Production
International Journal of Molecular Sciences
Rodrigues AF, Fernandes P, Laske T, Castro R, Alves PM, Genzel Y, Coroadinha AS
2020
Advanced Technologies for Gene Therapy Products
Establishing Suspension Cell Cultures for Improved Manufacturing of Oncolytic Adenovirus
Biotechnology Journal
Moreira AS, Silva AC, Sousa MFQ, Hagner-McWhirterc A, Ahlénc G, Lundgren M, Coroadinha AS, Alves PM, Peixoto C, Carrondo MJT
2020
Advanced Technologies for Gene Therapy Products
3D-printed ordered bed structures for chromatographic purification of enveloped and non-enveloped viral particles
Separation and Purification Technology
Moleirinho MG, Feast S, Moreira AS, Silva RJS, Alves PM, Carrondo MJT, Huber T, Fee C, Peixoto C
2020
Production of high-quality SARS-CoV-2 antigens: impact of bioprocess and storage on glycosylation, biophysical attributes, and ELISA serologic tests performance
Authorea, Inc.
Castro R, Nobre L, Eleutério R, Thomaz M, Pires A, Monteiro S, Mendes S, Gomes R, Clemente J, Sousa M, Pinto F, Silva A, Freitas M, Lemos A, Akpogheneta O, Kosack L, Bergman M‑L, Duarte N, Mastoso P, Costa J, Bandeiras T, Gomes‑Alves P, Gonçalves C, Demengeot J, Alves P
2020
Advanced Technologies for Gene Therapy Products
A Flow-Through Chromatographic Strategy for Hepatitis C Virus-Like Particles Purification
Processes
Silva RJS, Moleirinho MG, Moreira AS, Xenopoulos A, Alves PM, Carrondo MJT, Peixoto C
2020
Bioengineering for Cell-based Therapies
Towards a microencapsulated 3D hiPSC-derived in vitro cardiac microtissue for recapitulation of human heart microenvironment features
Frontiers in Bioengineering and Biotechnology
Abecasis B, Canhão PGM, Almeida HV, Calmeiro T, Fortunato E, Gomes-Alves P, Serra M, Alves PM
2020
Advanced Cell Models for Drug Discovery and Translational Research
Monocytes as Endothelial Progenitor Cells (EPCs), Another Brick in the Wall to Disentangle Tumor Angiogenesis
Cells
Lopes-Coelho F, Silva F, Gouveia-Fernandes S, Martins C, Lopes N, Domingues G, Brito C, Almeida AM, Pereira SA, Serpa J
2020
Advanced Cell Models for Drug Discovery and Translational Research
A computational diffusion model to study antibody transport within reconstructed tumor microenvironments
BMC Bioinformatics
Cartaxo AL, Almeida J, Gualda EJ, Marsal M, Loza-Alvarez P, Brito C, Isidro IA
2020
Advanced Technologies for Gene Therapy Products
Dielectric Spectroscopy to Improve the Production of rAAV Used in Gene Therapy
Processes
Pais DAM, Brown C, Neuman A, Mathur K, Isidro IA, Alves PM, Slade PG
2020
Advanced Technologies for Gene Therapy Products
Baculovirus affinity removal in viral-based bioprocesses
Separation and Purification Technology
Moleirinho MG, Fernandes RP, Carvalho SB, Bezemer S, Detmers F, Hermans P, Silva RJS, Alves PM, Carrondo MJT, Peixoto C
2020
Bioengineering for Cell-based Therapies
Bioreactor-based 3D human myocardial ischemia/reperfusion in vitro model: a novel tool to unveil key paracrine factors upon acute myocardial infarction
Translational Research
Sebastião MJ, Gomes-Alves P, Reis I, Sanchez B, Palacios I, Serra M, Alves PM
2020
Advanced Cell Models for Drug Discovery and Translational Research
A novel culture method that sustains ERα signaling in human breast cancer explants
Journal of Experimental & Clinical Cancer Research
Cartaxo AL, Estrada MF, Domenici G, Roque R, Silva F, Gualda EJ, Loza-Alvarez P, Sflomos G, Brisken C, Alves PM, André S, Brito C
2020
Advanced Cell Models for Drug Discovery and Translational Research
Patient-derived ovarian cancer explants: preserved viability and histopathological features in long-term agitation-based cultures
Scientific Reports
Abreu S, Silva F, Mendes R, Mendes TF, Teixeira M, Santo VE, Boghaert ER, Félix A, Brito C
2020
Bioengineering for Cell-based Therapies
Unveiling dynamic metabolic signatures in human induced pluripotent and neural stem cells
PLOS Computational Biology
Vasconcelos JS, Simão D, Terrasso AP, Silva MM, Brito C, Isidro IA, Alves PM, Carrondo MJT
2020
Advanced Technologies for Gene Therapy Products
Evaluation of Structurally Distorted Split GFP Fluorescent Sensors for Cell-Based Detection of Viral Proteolytic Activity
Sensors
Guerreiro MR, Fernandes AR, Coroadinha AS
2020
Holographic Imaging of Insect Cell Cultures: Online Non-Invasive Monitoring of Adeno-Associated Virus Production and Cell Concentration
Processes
Pais DAM, Galrão PRS, Kryzhanska A, Barbau J, Isidro IA, Alves PM
2020
Vaccines Bioprocess Engineering
Improving Influenza HA-Vlps Production in Insect High Five Cells via Adaptive Laboratory Evolution
Vaccines
Correia R, Fernandes B, Alves PM, Carrondo MJT, Roldao A
2020
Advanced Technologies for Gene Therapy Products
Overexpression of ER Protein Processing and Apoptosis Regulator Genes in Human Embryonic Kidney 293 Cells Improves Gene Therapy Vectors Production
Biotechnology Journal
Formas‐Oliveira AS, Basílio JS, Rodrigues AF, Coroadinha AS
2020
Advanced Technologies for Gene Therapy Products
Advances in lentivirus purification
Biotechnology Journal
Moreira AS, Cavaco D, Faria T, Alves PM, Carrondo MJT, Peixoto C
2020