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Biologics



biologics@ibet.pt

Explore R&D Services

Explore R&D Services

iBET has established a strong base of expertise and competences in the expression, production, purification, scaling up, analysis and characterization of biopharmaceuticals

We work with bioprocess development and scale up of Advanced Therapy Medicinal Products (ATMPs) such as gene therapy, somatic and stem cells, tissue-engineered medicines and vaccines (bacterial and viral)

WORKING ALONGSIDE YOU IN EVERY STEP OF THE PROCESS

iBET’s experience in bioprocess development and scale-up dates back to 1994 when the Pilot Plant Unit (now Late Stage R&D and Bioprocess Unit) started its operations. Since then, our team of highly-trained experts have been optimizing upstream and downstream processes in a broad range of products, e.g., Advanced Therapy Medicinal Products, vaccines, diagnostics and therapeutic products and recombinant proteins for structural biology studies.

Bioprocess Development and Scale Up Expertise include:

  • Optimization of scale up strategies for different industry relevant biotechnological process lines
  • Implementation of process control systems. Our control systems include integration of hardware and software, simulation and actual data, including expert systems and multivariate data analysis
  • Development of new and unique purification strategies
  • Identification of process engineering limitations
  • Development of cost effective, robust solutions based on your existing platform and product release specifications
  • Scale-up to 70L (50L working volume) in stirred tanks and 50L (25L working volume) in Wave bioreactors

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