Sofia Carvalho

Senior Scientist

sofiacarvalho@ibet.pt

Short Biography

I am a Senior Scientist at the Sanofi satellite laboratory within the Animal Cell Technology Unit of iBET’s Health & Pharma Division, where I have worked since 2018. My research is focused on downstream processes and bioanalytics development, namely on bioprocess understanding and biologics characterisation.

I am exploring how operating variables impact process performance and product quality, from mAbs to gene therapy products.

I hold a Biochemistry degree and MSc (2009, 2011) from Faculdade de Ciências, Universidade de Lisboa and a PhD in Biotechnology (2018) from ITQB-NOVA, in collaboration with iBET. My PhD was on Downstream processing strategies for Influenza VLPs as universal vaccine candidates, and on developing analytical tools for process optimization and product characterization. I did part of my PhD studies at the Max Planck Institute for the Dynamics of Complex Technical Systems, Downstream Processing Lab (Germany), and at PALL Life Sciences (UK).

In January 2018, I joined Genibet Biopharmaceuticals as a Project Manager, working on viral process development and cGMP manufacturing. Later that year, I returned to iBET, to integrate the Sanofi Satellite Lab team.

CV Highlights: author of 18 manuscripts, 1 conference paper and 1 book chapter garnering 450 citations (h-index 12). More than 20 oral presentations and 30 poster communications at national and international conferences. Supervision of students and research fellows. Team member in several publicly funded research projects (FCT and EC) and PI in 2 iBETXplore projects. Managed several R&D projects with the biopharma industry. Currently managing the Bioanalytics Scientific Committee, established in 2023