Publications

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SWATH-MS as a strategy for CHO host cell protein identification and quantification supporting the characterization of mAb purification platforms
Journal of Biotechnology
S B Carvalho, L Profit, S Krishnan, R A Gomes, B M Alexandre, S Clavier, M Hoffman, K Brower, P Gomes-Alves
2024
Natural Bioactives & Nutraceuticals
Compressed fluid-based technology for downstream isolation of bluish anthocyanin-derived pigments obtained from blueberry surplus
Food & Function
A N Nunes, J Oliveira, M R Bronze, A A Matias
2024
Microbiology and Molecular Biology
Whole genome sequence of Paracoccus sp. NFXS7, a carotenoid-producing bacterium isolated from a marine saltern
Access Microbiology
C D F Bertrand, R Martins, F Quintas-Nunes, P Reynolds-Brandão, M T B Crespo, F X Nascimento
2024
Natural Bioactives & Nutraceuticals
Unveiling the anti-inflammatory potential of 11β,13-dihydrolactucin for application in inflammatory bowel disease management
Food & Function
M S Matos, M A Ávila-Gálvez, A González-Sarrías, N V Silva, C L Crespo, A Jacinto, A T Serra, A A Matias, C N Dos Santos
2024
Vaccines Bioprocess Engineering
Production of high-quality SARS-CoV-2 antigens: Impact of bioprocess and storage on glycosylation, biophysical attributes, and ELISA serologic tests performance
Biotechnology and Bioengineering
R Castro, LS Nobre, RP Eleutério, M Thomaz, A Pires, SM Monteiro, S Mendes, RA Gomes, JJ Clemente, MFQ Sousa, F Pinto, AC Silva, MC Freitas, AR Lemos, O Akpogheneta, L Kosack, M-L Bergman, N Duarte, P Matos, J Costa, TM Bandeiras, P Gomes-Alves, CP Gonçalves, J Demengeot, PM Alves
2021
Vaccines Bioprocess Engineering
Process intensification for Peste des Petites Ruminants Virus vaccine production
 Vaccine
M Sousa , C Fenge, J Rupprecht, A Tappe, G Greller, P M Alves, M J T Carrondo, A Roldão
2019
Advanced Technologies for Gene Therapy Products
AAV process intensification by perfusion bioreaction and integrated clarification
 Frontiers in Bioengineering and Biotechnology
João P. Mendes, B Fernandes, E Pineda, S Kudugunti, M Bransby, R Gantier, C Peixoto, P M Alves, A Roldão, R J S Silva
2022
Vaccines Bioprocess Engineering
Development of versatile affinity-based system for one step purification process: Case of Group A Streptococcus vaccine
Biotechnology and Bioengineering
A Chevrel, L Candela, E Innocenti, C Golibrzuch, R Skudas, A Schwämmle, M J T Carrondo, O Kitten, M Nissum, R J S Silva
2022
Advanced Technologies for Gene Therapy Products
Continuous Affinity Purification of Adeno-Associated Virus Using Periodic Counter-Current Chromatography
Pharmaceutics
J P Mendes,M Bergman,A Solbrand,C Peixoto, M J T Carrondo, R J S Silva
2022
Advanced Technologies for Gene Therapy Products
Advances in lentivirus purification
Biotechnology Journal
AS Moreira, DG Cavaco, TQ Faria, PM Alves, MJT Carrondo, C Peixoto
2021
Advanced Technologies for Gene Therapy Products
LentiPro26: novel stable cell lines for constitutive lentiviral vector production.
Natura Scientific Reports
HA Tomás, A F Rodrigues, M J T Carrondo MJT, A S Coroadinha
2018
Advanced Technologies for Gene Therapy Products
Improved GaLV-TR Glycoproteins to Pseudotype Lentiviral Vectors: Impact of Viral Protease Activity in the Production of LV Pseudotypes
Molecular Therapy - Methods & Clinical Development
H A Tomás, D A Mestre, A F Rodrigues, M R Guerreiro, M J T Carrondo, A S Coroadinha
2019
Advanced Technologies for Gene Therapy Products
Progress and Perspectives in the Development of Lentiviral Vector Producer Cells
Biotechnology Journal
M V Ferreira, E T Cabral, A S Coroadinha
2021
Advanced Technologies for Gene Therapy Products
Implementation of Novel Affinity Ligand for Lentiviral Vector Purification
International Journal of Molecular Sciences
A S Moreira, S Bezemer, T Q Faria, F Detmers, P Hermans, L Sierkstra, A S Coroadinha, C Peixoto
2023
Advanced Technologies for Gene Therapy Products
Towards a scalable bioprocess for rAAV production using a HeLa stable cell line
Biotechnology and Bioengineering
J Escandell, F Moura, S B Carvalho, R J S Silva, R Correia, A Roldão, P Gomes-Alves, P M Alves
2023
Advanced Technologies for Gene Therapy Products
Efficient adeno-associated virus serotype 5 capture with affinity functionalized nanofiber adsorbents
Frontiers in Bioengineering and Biotechnology
S Neto, J P Mendes, S B Dos Santos, A Solbrand, M J T Carrondo, C Peixoto, R J S Silva
2023
Advanced Cell Models for Drug Discovery and Translational Research
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation.
Stem Cell Reports
Simão D, Silva MM, Terrasso AP, Arez F, Sousa MFQ, Mehrjardi NZ, Šarić T, Gomes-Alves P, Raimundo N, Alves PM, Brito C
2018
Advanced Cell Models for Drug Discovery and Translational Research
Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection
ACS Infect Dis.
F Arez, SP Rebelo, D Fontinha, D Simão, TR Martins, M Machado, C Fischli, C Oeuvray, L Badolo, MJT Carrondo, M Rottmann, T Spangenberg, C Brito, B Greco, M Prudêncio, PM Alves
2019
Advanced Cell Models for Drug Discovery and Translational Research
A novel culture method that sustains ERα signaling in human breast cancer explants
Journal of Experimental & Clinical Cancer Research
A L Cartaxo, M Estrada, G Domenici, R Roque, F Silva, E G Gualda, P Loza-Alvarez, G Sflomos, C Brisken, P M Alves, S André, C Brito
2020
Advanced Cell Models for Drug Discovery and Translational Research
Capturing the third dimension in drug discovery: spatially resolved tools for interrogation of complex 3D cell models
Biotechnology Advances
D Simão, C M Gomes, P M Alves, C Brito
2022
Advanced Cell Models for Drug Discovery and Translational Research
Tackling the tumor microenvironment - how can complex tumor models in vitro aid oncology drug development?
Expert Opinion in Drug Discovery
M C Cox, R Mendes, K N Halwachs, G Domenici, C Brito, E R Boghaert
2023
Advanced Cell Models for Drug Discovery and Translational Research
Immune microenvironment dynamics of HER2 overexpressing breast cancer under dual anti-HER2 blockade
Frontiers in Bioengineering and Biotechnology
S Batalha, C M Gomes, C Brito
2023
Advanced Cell Models for Drug Discovery and Translational Research
Miniaturization of hiPSC-derived 3D neural cultures in stirred-tank bioreactors for parallelized preclinical assessment of rAAV
Frontiers in Bioengineering and Biotechnology
C M Gomes, M J Sebastião, G Silva, F Moura, D Simão, P Gomes-Alves, P M Alves, C Brito
2024
Natural Bioactives & Nutraceuticals
Saffron against Neuro-Cognitive Disorders: An Overview of Its Main Bioactive Compounds, Their Metabolic Fate and Potential Mechanisms of Neurological Protection
Nutrients
D Cerdá-Bernad, L Costa, A T Serra, M R Bronze, E Valero-Cases, F Pérez-Llamas, M E Candela, M B. Arnao, F T Barberán, R G Villalba, MT García-Conesa, M J Frutos
2022