Publications

Filters
Protein Biophysics for Drug Discovery
An engineered cereblon optimized for high-throughput screening and molecular glue discovery
Cell Chemical Biology
Bailey HJ, Eisert J, Kazi R, Gerhartz J, Pieńkowska DE, Dressel I, Vollrath J, Kondratov I, Matviyuk T, Tolmachova N, Shah VJ, Giuliani G, Mosler T, Geiger TM, Esteves AM, Santos SP, Sousa RL, Bandeiras TM, Leibrock EM, Bauer U, Leuthner B, Langer JD, Wegener AA, Nowak RP, Sorrell FJ, Dikic I
2025
Bioengineering for Cell-based Therapies
Heterotypic spheroids as a strategy for 3D culture of cryopreserved primary human hepatocytes in stirred-tank systems
SLAS Discovery
Arez F, Preiss L, Ramella Gal I, Rebelo SP, Badolo L, Brito C, Spangenberg T, Alves PM
2025
Vaccines Bioprocess Engineering
Virus-like particle vaccine with authentic quaternary epitopes protects against Zika virus-induced viremia and testicular damage
Journal of Virology
Abbo SR, Yan K, Geertsema C, Hick TAH, Altenburg JJ, Nowee G, van Toor C, van Lent JW, Nakayama E, Tang B, Metz SW, Bhowmik R, de Silva AM, Prow NA, Correia R, Alves PM, Roldão A, Martens DE, van Oers MM, Suhrbier A, Pijlman GP
2025
Advanced Technologies for Gene Therapy Products
Deciphering Key Adenoviral Elements in the Production of Recombinant Adeno-Associated Virus Vectors
Human Gene Therapy
Fernandes S, Guerra J, Ferreira MV, Coroadinha AS
2025
Vaccines Bioprocess Engineering
Continuous Production of Influenza VLPs Using IC‐BEVS and Multi‐Stage Bioreactors
Biotechnology and Bioengineering
Correia R, Zotler T, Ferraz F, Fernandes B, Graça M, Pijlman GP, Alves PM, Roldão A
2025
Vaccines Bioprocess Engineering
Modifying the glycosylation profile of SARS-CoV-2 spike-based subunit vaccines alters focusing of the humoral immune response in a mouse model
Communications Medicine
Renner TM, Stuible M, Rossotti MA, Rohani N, Cepero-Donates Y, Sauvageau J, Deschatelets L, Dudani R, Harrison BA, Baardsnes J, Koyuturk I, St. Michael F, Hill JJ, Hemraz UD, Lenferink AEG, Tanha J, Fernandes B, Roldao A, McCluskie MJ, Akache B, Durocher Y
2025
Natural Bioactives & Nutraceuticals
Optimization of Supercritical Fluid Extraction for the Recovery of γ-Oryzanol-Rich Extracts with Improved Bioactivity from Rice Bran
Antioxidants
Baixinho JP, Cardeira M, Bento-Silva A, Partidário AMC, Serra AT, Bronze MR, Fernández N
2025
Microbiology and Molecular Biology
Beyond guaiacol and halophenols: Unravelling isobutyric and isovaleric acids as new culprits in off-flavour spoilage by Alicyclobacillus spp.
International Journal of Food Microbiology
Leonardo IC, Ferreira A, Bronze MR, Quendera AP, Fernandes AF, Barreto Crespo MT, Bustos Gaspar F
2025
Advanced Technologies for Gene Therapy Products
Purification of AAV8 through a scalable two-step monolithic chromatography approach
Journal of Chromatography A
Nascimento A, Faria TQ, Bollmann F, Noverraz M, Pressac G, Roldão A, Peixoto C, Silva RJS
2025
Microbiology and Molecular Biology
Integration of spectroscopic techniques and machine learning for optimizing Phaeodactylum tricornutum cell and fucoxanthin productivity
Bioresource Technology
Reynolds-Brandão P, Quintas-Nunes F, Bertrand CF, Martins RM, Crespo MTB, Galinha CF, Nascimento FX
2025
Natural Bioactives & Nutraceuticals
Collagen–Chitosan Composites Enhanced with Hydroxytyrosol for Prospective Wound Healing Uses
Pharmaceutics
Batista MP, Pimenta M, Fernández N, Duarte ARC, Bronze MR, Marto J, Gaspar FB
2025
Bioengineering for Cell-based Therapies
Billion‐Scale Expansion of Functional hiPSC‐Derived Cardiomyocytes in Bioreactors Through Oxygen Control and Continuous Wnt Activation
Advanced Science
Vicente P, Inocêncio LR, Ullate‐Agote A, Louro AF, Jacinto J, Gamelas B, Iglesias‐García O, Martin‐Uriz PS, Aguirre‐Ruiz P, Ríos‐Muñoz GR, Fernández‐Santos ME, van Mil A, Sluijter JPG, Prósper F, Mazo MMV, Alves PM, Serra M
2025
Advanced Technologies for Gene Therapy Products
Deciphering key parameters enhancing lentiviral vector producer cells yields: Vector components copy number and expression
Molecular Therapy Methods & Clinical Development
Formas-Oliveira AS, Ferreira MV, Coroadinha AS
2025
Natural Bioactives & Nutraceuticals
Unveiling the anti-inflammatory potential of 11β,13-dihydrolactucin for application in inflammatory bowel disease management
Food & Function
M S Matos, M A Ávila-Gálvez, A González-Sarrías, N V Silva, C L Crespo, A Jacinto, A T Serra, A A Matias, C N Dos Santos
2024
Microbiology and Molecular Biology
Sustainable production of nanoemulsions by membrane-assisted nanoemulsification using novel aroma-based hydrophobic deep eutectic solvents for enhanced antifungal activities.
Journal of Cleaner Production
S Mondal, U T Syed, E Pinto, I C Leonardo, P Romero, F B Gaspar, M T Barreto Crespo, V Sebastian, J G Crespo, C Brazinha
2024
Microbiology and Molecular Biology
Beyond Harmful: Exploring Biofilm Formation by Enterococci Isolated from Portuguese Traditional Cheeses
Foods
Serrano, S.; Ferreira, M. V.; Alves-Barroco, C.; Morais, S.; Barreto-Crespo, M. T.; Tenreiro, R.; Semedo-Lemsaddek, T.
2024
Natural Bioactives & Nutraceuticals
CO2-Based Encapsulation of Rutin-Rich Extracts from Black Elderberry Waste Using Advanced PGSS Process
Foods
Mutavski, Z.; Vidović, S.; Ambrus, R.; Šavikin, K.; Baixinho, J.; Fernández, N.; Nastić, N.
2024
Natural Bioactives & Nutraceuticals
A Novel Collagen Aerogel with Relevant Features for Topical Biomedical Applications
ChemPlusChem
Batista, Miguel P. and Schroeter, Baldur and Fernández, Naiara and Gaspar, Frédéric Bustos and do Rosário Bronze, Maria and Duarte, Ana Rita and Gurikov, Pavel
2024
Circulating low-molecular-weight (poly)phenol metabolites in the brain: unveiling in vitro and in vivo blood–brain barrier transport
Food & Function
Carecho, R.; Marques, D.; Carregosa, D.; Masuero, D.; Garcia-Aloy, M.; Tramer, F.; Passamonti, S.; Vrhovsek, U.; Ventura, M. R.; Brito, M. A.; Nunes dos Santos, C.; Figueira, I.
2024
Towards detection of structurally-diverse glycated epitopes in native proteins: Single-chain antibody directed to non-A1c epitope in human haemoglobin
Molecular Immunology
Gaetani, Miss Lucia and Pinto, Isabel Campos and Li, Meng and O’Connor, Peter and Giorgi-Coll, Susan and Tyreman, Matthew and Rumary, Katherine L. and Schouten, James A. and Davis, Paul and Dixon, Ann M.
2024
Microbiology and Molecular Biology
Whole genome sequences of marine bacteria presenting the ability to promote the growth of the diatom Phaeodactylum tricornutum
Microbiology Society
Martins, R.; Bertrand, C.; Quintas-Nunes, F.; Reynolds-Brandão, P.; Barreto Crespo, M.; Nascimento, F. X.
2024
Bioengineering for Cell-based Therapies
Oxygen control in bioreactor drives high yield production of functional hiPSC-like hepatocytes for advanced liver disease modelling
Scientific Reports
Vicente, Pedro and Almeida, Joana I. and Crespo, Inês E. and Virgolini, Nikolaus and Isidro, Inês A. and Calleja-Cervantes, Maria Eréndira and Rodriguez-Madoz, Juan R. and Prosper, Felipe and Alves, Paula M. and Serra, Margarida
2024
Protein Biophysics for Drug Discovery
The HSP90/R2TP Quaternary Chaperone Scaffolds Assembly of the TSC Complex
Journal of Molecular Biology
Abéza, C.; Busse, P.; Paiva, A. C. F.; Chagot, M.-E.; Schneider, J.; Robert, M.-C.; Vandermoere, F.; Schaeffer, C.; Charpentier, B.; Sousa, P. M. F.; Bandeiras, T. M.; Manival, X.; Cianferani, S.; Bertrand, E.; Verheggen, C.
2024
Microbiology and Molecular Biology
Viral pathogen surveillance in wastewater using metagenomic approaches: obstacles and prospects
European Journal of Public Health
Seabra, S. G.; Santos, A. F.; Nunes, M.; Manjate, F.; Silva, A.; Crespo, T.; Pimentel, V.; Libin, P.; Abecasis, A. B.; Parreira, R.
2024