Modeling Cardiac Fibrosis: iBET’s Latest Research Awarded at International Conference

Impact of Monocyte-Derived Macrophages on Cardiac Fibroblast Activation

Pedro Coelho presented recent work on modeling cardiac fibrosis at the 4th International Conference on Tissue Repair, Regeneration and Fibrosis by Aegean Conferences, in Crete, Greece, from October 22nd-26th.

Supported by iBET’s internal innovation program, iBETXplore, this research work aims to identify pro-fibrotic macrophage phenotypes capable of activating cardiac fibroblasts, which can exacerbate fibrosis in myocardial infarction cases.

The project’s end goal is to develop CAR-T cells specifically designed to target these pro-fibrotic macrophages, thereby controlling their role in cardiac fibroblasts activation and reducing fibrosis in affected patients.

Pedro Coelho’s poster presentation, titled “Modeling cardiac fibrosis in vitro: impact of monocyte-derived macrophages on cardiac fibroblast activation”, earned a Travel Award Grant for being among the Top 3 Student Best Poster Presentations, recognizing the quality of his presentation and overall contribution to the conference.

iBET extends its warmest congratulations to Pedro and remaining research team for this great achievement.