Late-Stage R&D and Bioproduction Unit Team
Late-stage R&D, scale-up and technology transfer for complex biopharmaceuticals production.
Research Focus
At iBET’s Late-stage R&D and Bioproduction Unit, we are dedicated to advancing bioprocess solutions for some of the most complex biopharmaceuticals.
Our work spans a diverse range of modalities, including viral vectors such as adeno-associated virus (AAVs), oncolytic or chimeric viruses, recombinant proteins like virus-like particles (VLPs), next-generation antibodies (e.g. bi- and tri-specific formats), and difficult-to-express antigens, including antibody fragments and receptor domains.
The team has been reinforcing iBET’s leadership in these areas, nationally and internationally, while also fostering interaction amongst iBET Units/laboratories and the training of specialized researchers and technicians. Most recent activities have been centered on the design of robust solutions for product expression, purification and characterization, process scale-up (up to 50 L), and technology transfer to GMP environments.
For more details, please visit our dedicated Late-Stage R&D and Bioproduction Unit page.
Areas of Activity
Late-stage R&D
We design and optimize upstream and downstream processes, integrating advanced bioanalytical tools and continuous bioprocessing strategies to ensure robust performance and product quality.
Bioprocess Scale-up
We translate lab-scale processes into scalable, GMP compliant processes for production and purification of complex biopharmaceuticals.
Technology Transfer
We deliver seamless transfer to CDMOs through comprehensive documentation, SOP development, and on-site shadowing of key process operations.
António Roldão
Head of Cell-based Vaccines Development Lab | Coordinator of Late-Stage R&D Unit
I am the Coordinator of the Late-Stage R&D Unit at iBET since 2021. In this role, I coordinate and/or manage multiple national and EU funded projects as well as R&D service driven projects focused on vaccines and viral vectors production.
Cristina Peixoto
Head of Downstream Process Development Lab | Coordinator of Bioproduction Unit
I coordinate the Bioproduction Unit at iBET since 2021. I have managed more than 50 R&D service driven projects with industrial partners, some of the processes developed are now at the clinical stage.
